Cardiovascular risk and BDNF concentration in vegetarians in the city of Sao Paulo – SP

Pimentel, Carolina Vieira de Mello Barros; Teodorov, Elizabeth; Simomura, Viviane Lazari; Rogero, Marcelo Macedo; Philippi, Sônia Tucunduva

doi:10.15406/jccr.2019.12.00457

Cited by 1 publication

(1 citation statement)

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“…In a study conducted in 2019 on 96 participants, CRI.I was considered as an index to predict cardiovascular risk among people in two diet groups, vegetarians and omnivores. In this study, CRI-I was signi cantly greater in omnivores than in vegetarians, and people who have higher adherence to a vegetarian diet elevate by 17 times the probability of having a normal CRI-I (103,104).…”

Section: Discussionmentioning

confidence: 51%

Interaction of Genetics Risk Score (GRS) and Plant-Based Diet on factors Atherogenic and body adiposity indexes among overweight and obese women: a cross-sectional study

Hajmir,

Mirzababaei,

Abaj

et al. 2024

Preprint

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Background: The association between plant-based foods with obesity, cardiovascular diseases (CVD), and their novel predictive biomarkers considering genetic predisposition remains uncertain. Given that diet is a significant and modifiable risk factor, we sought to investigate the interactions between plant-based diet and genetic susceptibility with atherogenic factors, and visceral and body adiposity indices in Iranian women. Methods: This cross-sectional study was conducted on 377 obese and overweight women, aged 18–48 from Iran. Using standard protocols, anthropometric indices, body composition, physical activity, and serum profiles were measured. A validated 147-item semi-quantitative food frequency questionnaire (FFQ) was used to create three plant-based diets including the overall plant-based diet index (PDI), healthy plant-based diet index (hPDI), and unhealthy plant-based diet index (uPDI). A genetic risk score (GRS) was calculated based on the risk alleles of the three BMI-related SNPs. The interaction between GRS and PDI was analyzed using a generalized linear model (GLM). Result There was a negative significant interaction between tertile 2 of PDI and moderate risk allele and high-risk alleles with AIP, TGy, LAP, and VAI compared to the low-risk allele (P-value < 0.05). There was a negative borderline significant interaction between tertile 2 of hPDI and moderate risk allele (P-value = 0.05) with ABSI compared to low-risk allele participants. There was a positive significant interaction between tertile 2 of uPDI and moderate risk allele with CRI.I (P-value = 0.03), CRI.II (P-value = 0.03) compared to low-risk allele participants. Also, there was a positive significant interaction between tertile 3 of uPDI and high-risk allele with ABSI (P-value = 0.02) compared to low-risk allele participants. Conclusion The present study provides evidence that interaction between PDI, hPDI, and uPDI with GSR is associated with atherogenic index and body composition. Prospective and interventional studies in different populations and ethnicities need to be conducted to further the knowledge about examining the interaction between PDI, hPDI, and uPDI with GSR are associated with atherogenic index and body composition.

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Section: Discussionmentioning

confidence: 51%

Interaction of Genetics Risk Score (GRS) and Plant-Based Diet on factors Atherogenic and body adiposity indexes among overweight and obese women: a cross-sectional study

Hajmir,

Mirzababaei,

Abaj

et al. 2024

Preprint

View full text Add to dashboard Cite

show abstract

Cardiovascular risk and BDNF concentration in vegetarians in the city of Sao Paulo – SP

Abstract: BDNF is a basic protein, a member of the neurotrophin family, and which plays an essential role in neurobiology, as it positively interferes in brain neuroplasticity and, in particular, in neural survival,

Cited by 1 publication

References 52 publications

Interaction of Genetics Risk Score (GRS) and Plant-Based Diet on factors Atherogenic and body adiposity indexes among overweight and obese women: a cross-sectional study

Interaction of Genetics Risk Score (GRS) and Plant-Based Diet on factors Atherogenic and body adiposity indexes among overweight and obese women: a cross-sectional study

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