“…Moreover, other factors potentially associated with QTc prolongation, such as alcohol intake (Zhang et al, 2011) and illicit substances misuse (Devlin and Henry, 2008), are highly prevalent among subjects suffering from mental disorders (Carrà et al, 2015). An extensive use of concurrent drugs due to poor physical health (e.g., Carrà et al, 2014;Clerici et al, 2014) and high rates of comorbid alcohol or substance abuse (Carrà et al, 2006) are common among people with severe mental illnesses. Nonetheless, despite the increasing number of drugs associated with QTc prolongation (Nachimuthu et al, 2012), there have been no studies exploring the role of clinical factors along the path of the association between FGAs and QTc prolongation so far.…”