Cardiovascular risk factors and major depressive disorder: a cross-sectional study in São Paulo, Brazil

Bivanco-Lima, Danielle; Santos, Itamar S.; Wang, Yuan‐Pang; Viana, María Carmen; Andrade, Laura Helena; Lotufo, Paulo A.

doi:10.1590/1516-3180.2020.0054.r1.1802021

Cited by 3 publications

(2 citation statements)

References 47 publications

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“…Te animals' body weight, food intake, and deaths were registered every 2 days. On the 15 th day after the treatment, they were euthanized by inhalation of isofurane (dose of 10-12% in inhaled air) and confrmation by cervical displacement [34]; CONCEA [35] and the organs (liver, kidneys, adrenal glands, spleen, lungs, heart, and brain) relative weight (%) and macroscopic aspect were registered.…”

Section: Acute Toxicitymentioning

confidence: 99%

Anti‐Inflammatory and Antimicrobial Effects of Eucalyptus spp. Essential Oils: A Potential Valuable Use for an Industry Byproduct

Salvatori,

Morgan,

Ferrarini

et al. 2023

Evidence-Based Complementary and Alternative Medicine

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In Brazil, the use of Eucalyptus is focused on the production of wood or pulp for the paper industry but without any general recovery of waste, with leaves and branches being left on the ground. One possibility is to use these residues as raw materials in the production of industrially relevant and value-added compounds such as essential oil. The aim of the present study was to investigate the chemical composition, yield, anti-inflammatory/antinociceptive activities, and acute toxicity in mice, as well as the antimicrobial effects of essential oils from the leaves of 7 varieties of Eucalyptus and hybrids against Escherichia coli, Staphylococcus aureus, and Candida albicans. The extraction of oils was carried out using hydrodistillation, and they were analyzed by gas chromatography coupled to mass spectrometry. Urocam and Grancam were the plants that obtained the highest oil yield, with yields of 3.32 and 2.30%, respectively. The main chemical components identified in these plants were 1.8 cineole and α-pinene. The antinociceptive effect of the 7 oils (50 mg/kg, p.o.) was initially assessed in the acetic acid-induced writhing test. In this assay, a significant ( p < 0.05) antinociceptive/anti-inflammatory effect was observed from 4 tested essential oils (E. benthamii, E. saligna, and the hybrids Urocam and Grancam) when compared to the vehicle-treated group. This effect was then confirmed in the formalin-induced paw licking test. No toxicological effects or alterations were observed in motor coordination after the administration of the studied oils to the animals. In the antimicrobial evaluation, the seven essential oils inhibited the growth of S. aureus, E. coli, and C. albicans at different concentrations. Collectively, these results demonstrate that the essential oil from the leaves and branches of Eucalyptus species and varieties present potential biomedical applications and represent a source of antimicrobial and/or anti-inflammatory compounds.

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Section: Acute Toxicitymentioning

confidence: 99%

Anti‐Inflammatory and Antimicrobial Effects of Eucalyptus spp. Essential Oils: A Potential Valuable Use for an Industry Byproduct

Salvatori,

Morgan,

Ferrarini

et al. 2023

Evidence-Based Complementary and Alternative Medicine

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show abstract

“…There is evidence that both patients with depression are more likely to suffer from chronic diseases 21 , and that patients with chronic diseases are more prone to depression 22 . In the case of cardiovascular diseases and depression, it is believed that risk factors act as mediators 23 . Patients diagnosed with a chronic disease, upon realizing the chronic nature of their condition or when complications arise, may develop mental disorders such as depressive episodes 24 .…”

Section: Introductionmentioning

confidence: 99%

Urban environmental noise and depression causal pathway: Potential role of chronic conditions as mediator

Olea,

Hernández,

Suarez

et al. 2024

Preprint

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Accepting the fact of a growing urban population and associated health risks, such as increased exposure to pollutants, and considering the high prevalence of chronic diseases, this study aims to investigate the relationship between exposure to environmental noise and depression. The primary objective is to determine the potential mediating role of chronic diseases in this relationship. This study is part of the European H2020 URBANOME project, designed to explore the relationship between the environment and health in urban settings. The main goal of the project is to promote urban health, well-being, and liveability by systematically integrating health concerns into urban policies and civic activities. We obtained the data for this study from the Madrid City Health Survey, conducted through computer-assisted telephone interviews. Outcome variables assessed through self-reports included depression, exposure to environmental noise, and the presence of chronic diseases. We used a counterfactual mediation framework, implemented by the R package multimediate, to evaluate the potential mediating role of chronic diseases in the relationship between exposure to environmental noise and depression. The study included 8,445 interviews, with a higher percentage of women (54.67%) than men. 23.29% were over 65, and 17.17% under 30. Notably, 7.82% reported depression, 39.53% had chronic diseases, and 35.43% acknowledged noise exposure. In our regression model, those exposed to environmental noise were 1.24 times more likely to have a chronic disease, and individuals with a chronic disease were 2.93 times more likely to suffer from depression. The relationship between noise exposure and depression showed a 12% mediation by chronic diseases, with a 95% confidence interval from 5% to 22%. Our findings suggest a link between environmental noise exposure and depression, potentially mediated by chronic diseases. This points out the need for public health interventions to reduce urban noise exposure and improve mental health. Furthermore, prospective studies are needed for confirmation, incorporating noise level measurements and temporal data on the onset of chronic diseases and depression.

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Alcohol Consumption and Smoking Increased Risk of Developing Depressive Disorder beyond Gender Effect among Cardio Vascular Diseases Risk Factors

Kim,

Lee,

Jung

et al. 2024

Int J Ment Health Addiction

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Cardiovascular risk factors and major depressive disorder: a cross-sectional study in São Paulo, Brazil

Cited by 3 publications

References 47 publications

Anti‐Inflammatory and Antimicrobial Effects of Eucalyptus spp. Essential Oils: A Potential Valuable Use for an Industry Byproduct

Anti‐Inflammatory and Antimicrobial Effects of Eucalyptus spp. Essential Oils: A Potential Valuable Use for an Industry Byproduct

Urban environmental noise and depression causal pathway: Potential role of chronic conditions as mediator

Alcohol Consumption and Smoking Increased Risk of Developing Depressive Disorder beyond Gender Effect among Cardio Vascular Diseases Risk Factors

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