Cardiovascular Risk Factors and Perioperative Myocardial Infarction After Noncardiac Surgery

Tranexamic Acid in Patients Undergoing Noncardiac Surgery

“…1,7 Race or ethnic group Studies suggest non-white patients represent up to 25% of patients undergoing noncardiac surgery, in the United States. 8,9 Geography Patients undergoing noncardiac surgery in low and middle-income countries tend to be younger and with less comorbidities than in high-income countries. 6 Other considerations Of the >300 million surgeries that occur annually, only 6% occur in the poorest third of the world.…”

Invasive dental treatment and acute vascular events: A systematic review and meta‐analysis

“…A separate unanswered question is whether individuals who already suffer from a medical condition might be at a greater risk of AVEs when facing an acute inflammatory status or infection. A large retrospective cohort study (Wilcox et al, 2021) ( n = 3,848,501) confirmed that the 30‐day event rate of perioperative MI increased in a step‐wise manner with the presence of additional CVD risk factors (0.41% for one, 0.81% for two, and 1.07% for three; p < .001) (Wilcox et al, 2021). Similar evidence was reported on the effect of periodontitis and its treatment on the risk of PAD (Yang et al, 2018; Aarabi et al, 2020).…”

The Silent Burden of Perioperative Myocardial Infarction After Noncardiac Surgery

“…In this issue of the Canadian Journal of Cardiology, Wilcox and colleagues report the results of an analysis using administrative data to perform a retrospective cohort study of 3,848,501 patients who underwent noncardiac surgery between 2009 and 2015 in the United States, to identify predictors of perioperative MI. 8 They included patients 18 years of age and older who underwent major noncardiac surgery in the inpatient and outpatient settings. Postoperative MI was diagnosed in 0.37% of patients, and 1.04% of patients died.…”

“…Dr Wilcox and colleagues have made an important contribution to the current literature by identifying that hypertension, smoking, and diabetes might easily identify patients at risk of postoperative MI. 8 Moreover, they have provided important insights regarding the relationship between the severity of smoking exposure and severity of diabetes and the risk of perioperative MI. Prospective large cohort studies with active postoperative troponin measurements to identify myocardial injury are needed to validate their findings.…”

“…Dr Wilcox and colleagues have provided important data to help identify patients at risk of a perioperative MI that trialists will find helpful. 8…”