Cardiovascular Risk Factors and Sudden Sensorineural Hearing Loss: A Case-Control Study

Abstract

ObjectiveTo investigate the role of cardiovascular risk factors (specifically hypertension [HTN], hyperlipidemia/dyslipidemia, diabetes mellitus I and II, and body mass index (BMI) on the development of sudden sensorineural hearing loss (SSNHL).Study DesignCase-control retrospective chart review.SettingA tertiary referral center.PatientsPatients aged 18 to 85 years who presented to the clinic over a 1-year span (September 17, 2020 to September 17, 2021) for evaluation of sudden sensorineural hearing loss.Main Outcome MeasureComparing the prevalence of the different cardiovascular risk factors (CVRFs) in patients with sudden sensorineural hearing loss compared with when compared with non-SSNHL patients at a neurotology clinic.ResultsTwo hundred twenty-three patients with SSNHL were compared with age- and gender-matched comparison group to investigate the prevalence of cardiovascular risk factors within each group. There are no statistically significant differences (p > 0.05) in the prevalence of HTN, hyperlipidemia/dyslipidemia, diabetes mellitus I and II, and BMI in patients with sudden sensorineural hearing loss when compared with non-SSNHL patients at a neurotology clinic.ConclusionsDespite correlation between CVRF and SSNHL found in some other studies, we did not find a significant correlation between CVRF (diabetes, HTN, dyslipidemia, and high BMI) and SSNHL in our retrospective case control study of patients presenting to a nonacademic tertiary neurotology clinic. Although there may be other factors contributing to the pathogenesis of SSNHL, we have not yet identified these factors.

Correlation of Apo B/A1 ratio with hemodynamics and hearing impairment degree in elderly patients with sudden sensorineural hearing loss

“…Because this artery has no collateral circulation, once thrombosis or vasospasm occurs, it will lead to ear ischemia, hypoxia, microcirculation disturbance, further damage to the inner ear, and even irreversible deafness [ 21 ]. Clinical research showed that, vascular disease plays a very important role in SSNHL, and cochlear microcirculation disorder caused by vascular diseases is a common cause of SSNHL [ 22 , 23 ]. The results of this study showed that the levels of hemodynamic indexes in patients with SSNHL was significantly higher than that of healthy subjects, and the levels of hemodynamic indicators were gradually increased with the increased degree of hearing loss, which were significantly correlated with the degree of hearing loss in patients.…”

Relationship between midfacial fractures and maxillary sinus pathology

“…The maxillary sinus is primarily supplied with blood through branches of the maxillary artery, including the posterior lateral nasal artery, the infraorbital artery, and the posterior superior alveolar artery. The maxillary sinus and its mucosa are primarily innervated by the maxillary division of the trigeminal nerve [ 9 ]. The maxillary sinus is one of the frequently injured anatomical sites in midfacial fractures.…”

Exploring Audiologic Outcomes in Sudden Sensorineural Hearing Loss: A Retrospective Analysis

“…Furthermore, cholesterol levels were higher in patients with SSNHL compared to controls, but no significant associations were found for smoking, HDL, LDL, triglyceride, or BMI [8]. In contrast, two studies found no association between SSNHL and comorbidities such as hypertension and diabetes, as well as smoking and drinking habits [9,10] or hyperlipidemia [10]. Alternatively, one study found higher levels of leukocytes, neutrophils, neutrophil-tolymphocyte ratio, and fibrinogen in patients with SSNHL [9].…”