Cardiovascular risk factors in the Japanese northeastern rural population

Ohsawa, Masaki; Itai, Kazuyoshi; Tanno, Kozo; Onoda, Toshiyuki; Ogawa, Akira; Nakamura, Motoyuki; Kuribayashi, Toru; Yoshida, Yuki; Kawamura, Kazuko; Sasaki, Satoshi; Sakata, Kiyomi; Okayama, Akira

doi:10.1016/j.ijcard.2008.06.052

Cited by 43 publications

(37 citation statements)

References 26 publications

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“…In a large cardiovascular cohort study in Iwate Prefecture, the registrants from the general population showed higher values of blood pressure and HbA1c, higher incidences of hypertension and diabetes mellitus in the elderly, higher incidences of hypertension and diabetes mellitus, and higher incidences of past history of cardio-and cerebrovascular diseases in men. 24 These background characteristics of the general population in Iwate may explain the higher incidence of cerebrovascular disease in elderly men in the high flooding area in Iwate Prefecture.…”

Section: Discussionmentioning

confidence: 99%

Influence of the Great East Japan Earthquake and Tsunami 2011 on Occurrence of Cerebrovascular Diseases in Iwate, Japan

Omama

Yoshida

Ogasawara

et al. 2013

Stroke

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Section: Discussionmentioning

confidence: 99%

Influence of the Great East Japan Earthquake and Tsunami 2011 on Occurrence of Cerebrovascular Diseases in Iwate, Japan

Omama

Yoshida

Ogasawara

et al. 2013

Stroke

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“…10,11) In brief, the original cohort (n = 26,469) was recruited from the population living in Ninohe, Kuji, and Miyako districts of northern Iwate prefecture, Japan, during [2002][2003][2004]. Of the original cohort living in Ninohe and Kuji districts (n = 15,927), 15,394 subjects (97%) underwent BNP measurement (BNP cohort: men 5,288; women 10,106).…”

Section: Methodsmentioning

confidence: 99%

Plasma B-Type Natriuretic Peptide Is Useful for Cardiovascular Risk Assessment in Community-Based Diabetes Subjects

et al. 2012

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SummaryDiabetes mellitus (DM) is a strong risk factor for cardiovascular (CV) disease. Plasma B-type natriuretic peptide (BNP) levels are elevated in various types of cardiac diseases. Increased plasma BNP levels have been reported to be associated with CV risk in apparently healthy individuals. However, no studies have yet examined the specific value of plasma BNP for predicting CV incidence in unselected DM subjects in a community-based population.In a community-based DM cohort (n = 1,059, mean = 66 years), baseline BNP levels were determined, and CV events were followed and captured prospectively. The cohort was divided by plasma BNP quintiles. The Cox proportional hazard model was used to determine the relative hazard ratios (HR) among the quintiles. In addition, the effects of adding the plasma BNP or urine albumin-to-creatinine ratio (UACR) to an established CV risk scoring model was examined by calculating the area under the receiver operating characteristic (ROC) curve (AUC).During the 5.7 year follow-up period, CV events were identified in 65 of the DM cohort. There was a significant association between plasma BNP levels and CV event rate (P < 0.001). HR was significantly increased in the highest quintile compared to the lowest (HR = 4.38; 95%CI 1.69 -11.84). The AUC generated from ROC analysis of the Framingham risk score for predicting general CV events was improved by adding BNP testing (from 0.66 to 0.74; P = 0.05), but not by adding UACR (from 0.66 to 0.67; P = 0.49).In a community sample of people with DM, plasma BNP levels above the 80 percentile are directly associated with CV risk, and measurement of plasma BNP alone or in conjunction with an established CV risk score is of value in predicting CV events in these subjects. (Int Heart J 2012; 53: 176-181)

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“…The methods for measuring serum lipid profile, plasma glucose level, and plasma glycosylated hemoglobin (HbA1c) have been previously described. 21 In this analysis, HbA1c level (National Glycohemoglobin Standardization Program [NGSP] equivalent value) was modified by adding 0.4% to the estimated value (the Japan Diabetes Society [JDS] value) according to the Guidelines of the JDS. 23 Urine albumin was assessed quantitatively using an immunonephelometric method (Nantiserum albumin, Dade Behring) and urine creatinine was measured quantitatively on enzymatic colorimetric test.…”

Section: Measurementsmentioning

confidence: 99%

Comparison of Predictability of Future Cardiovascular Events Between Chronic Kidney Disease (CKD) Stage Based on CKD Epidemiology Collaboration Equation and That Based on Modification of Diet in Renal Disease Equation in the Japanese General Population

Ohsawa

Tanno

Itai

et al. 2013

Circ J

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Cardiovascular risk factors in the Japanese northeastern rural population

Cited by 43 publications

References 26 publications

Influence of the Great East Japan Earthquake and Tsunami 2011 on Occurrence of Cerebrovascular Diseases in Iwate, Japan

Influence of the Great East Japan Earthquake and Tsunami 2011 on Occurrence of Cerebrovascular Diseases in Iwate, Japan

Plasma B-Type Natriuretic Peptide Is Useful for Cardiovascular Risk Assessment in Community-Based Diabetes Subjects

Comparison of Predictability of Future Cardiovascular Events Between Chronic Kidney Disease (CKD) Stage Based on CKD Epidemiology Collaboration Equation and That Based on Modification of Diet in Renal Disease Equation in the Japanese General Population

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