Cardiovascular risk in patients undergoing maintenance hemodialysis with Helixone® membrane: a multicenter randomized study

Dębska‐Ślizień, Alicja; Małgorzewicz, Sylwia; Dudziak, Maria; Książek, Andrzej; Sułowicz, Władysław; Grzeszczak, Władysław; Stanek-Piotrowska, Maria; Myśliwiec, Michał; Nowaczyk, Ryszard; Świetlik, Dariusz; Rutkowski, Bolesław

doi:10.20452/pamw.2495

Cited by 3 publications

(2 citation statements)

References 9 publications

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“…Current hemodialysis membranes have two main disadvantages. First, contact between the dialysis membrane and the blood can cause a series of blood stress cascades, and the dialysis membrane needs to have excellent biocompatibility 4,5 ; Second, the dialysis membrane is not effective in removing certain intermediate molecular weight toxins 6–9 …”

Section: Introductionmentioning

confidence: 99%

“…First, contact between the dialysis membrane and the blood can cause a series of blood stress cascades, and the dialysis membrane needs to have excellent biocompatibility 4,5 ; Second, the dialysis membrane is not effective in removing certain intermediate molecular weight toxins. [6][7][8][9] In recent years, coblending modification, surface functional group grafting, and surface coating have been frequently used to modify polymeric hemodialysis membranes. [10][11][12] The membranes used for hemodialysis include superhydrophilic membranes, bionic membranes, and mixed matrix membranes.…”

Section: Introductionmentioning

confidence: 99%

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Preparation and surface modification of ultrahigh throughput tannic acid coblended polyethersulfone ultrafiltration membranes for hemodialysis

Zhang

Feng

Wei

et al. 2023

J of Applied Polymer Sci

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Low dialysis and blood incompatibility efficiency are key issues to be addressed for polymeric hemodialysis membranes. To improve the comprehensive performance of hemodialysis membranes, polyethersulfone (PES)/tannic acid (TA) coblended ultrafiltration membranes were prepared and modified with a heparin-like functionalized TA coating. The coblended TA improved the pore structure of the PES ultrafiltration membrane. And it could also undergo π-π conjugation with the heparin-like functionalized TA in the modified solution, resulting in a greater abundance of modified groups loaded on the membrane surface and pores close to the surface. The modified coating further improved the membrane performance. The physicochemical properties, solute filtration, and blood compatibility properties of the membrane were tested. The effect of TA on the pore structure of the membrane and the presence of modified layers were demonstrated by morphological and chemical structure analyses. The final modified membrane had an ultrahigh water flux (1053 L/m 2 Áh), improved dialysis performance (BSA retention >99%, Lysozyme clearance >30% and Urea clearance >90%), and excellent hemocompatibility (The hemolysis rate was 1.31%, and APTT, PT, and TT values were increased by 40.8%, 74.2%, and 85.9%, respectively). This study shows that TA has great potential for improving the pore structure of polymeric membranes.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Preparation and surface modification of ultrahigh throughput tannic acid coblended polyethersulfone ultrafiltration membranes for hemodialysis

Zhang

Feng

Wei

et al. 2023

J of Applied Polymer Sci

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The biocompatibility and bioactivity of hemodialysis membranes: their impact in end-stage renal disease

et al. 2018

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Understanding Development of Malnutrition in Hemodialysis Patients: A Narrative Review

et al. 2020

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Hemodialysis (HD) majorly represents the global treatment option for patients with chronic kidney disease stage 5, and, despite advances in dialysis technology, these patients face a high risk of morbidity and mortality from malnutrition. We aimed to provide a novel view that malnutrition susceptibility in the global HD community is either or both of iatrogenic and of non-iatrogenic origins. This categorization of malnutrition origin clearly describes the role of each factor in contributing to malnutrition. Low dialysis adequacy resulting in uremia and metabolic acidosis and dialysis membranes and techniques, which incur greater amino-acid losses, are identified modifiable iatrogenic factors of malnutrition. Dietary inadequacy as per suboptimal energy and protein intakes due to poor appetite status, low diet quality, high diet monotony index, and/or psychosocial and financial barriers are modifiable non-iatrogenic factors implicated in malnutrition in these patients. These factors should be included in a comprehensive nutritional assessment for malnutrition risk. Leveraging the point of origin of malnutrition in dialysis patients is crucial for healthcare practitioners to enable personalized patient care, as well as determine country-specific malnutrition treatment strategies.

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Cardiovascular risk in patients undergoing maintenance hemodialysis with Helixone® membrane: a multicenter randomized study

Cited by 3 publications

References 9 publications

Preparation and surface modification of ultrahigh throughput tannic acid coblended polyethersulfone ultrafiltration membranes for hemodialysis

Preparation and surface modification of ultrahigh throughput tannic acid coblended polyethersulfone ultrafiltration membranes for hemodialysis

The biocompatibility and bioactivity of hemodialysis membranes: their impact in end-stage renal disease

Understanding Development of Malnutrition in Hemodialysis Patients: A Narrative Review

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