Cardioversion differences among first detected episode, paroxysmal, and persistent atrial fibrillation patients in the RHYTHM AF registry in Poland

Background In patients with paroxysmal atrial fibrillation (PAF) or persistent atrial fibrillation (PeAF) symptom burden and fear of hospital readmission are major causes of reduced quality of life. We attempted to develop a prediction model for future atrial fibrillation hospitalization (AFH) risk in PAF and PeAF patients including all previously experienced AFHs in the analysis, as opposed to time to first event. Methods Recurrent event survival analysis was used to model the impact of past AFHs on the risk of future AFHs. A recurrent event was defined as a hospitalization due to a new episode of AF. Death or progression to permanent AF were included as competing risks. Results We enrolled 174 patients with PAF or PeAF, mean follow up duration was 1279 days, and 325 AFHs were observed. Median patient age was 63.0 (IQR 52.2–68.0), 29% had PAF, and 71% were male. Highly significant predictors of future AFH risk were PeAF (HR 3.20, CI 2.01–5.11) and number of past AFHs observed (HR for 1 event: 2.97, CI 2.04–4.32, HR for ≥2 events: 7.54, CI 5.47–10.40). Conclusion In PAF and PeAF patients, AF type and observed AFH frequency are highly significant predictors of future AFH risk. The developed model enables risk prediction in individual patients based on AFH history and baseline characteristics, utilizing all events experienced by the patient. This is the first time recurrent event survival analysis has been used in AF patients.

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Features of diagnosis and treatment of newly diagnosed atrial fibrillation

Lependin,

Patsenko,

Surigina

et al. 2023

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Due to the wide spread in the population and high risk of complications, atrial fibrillation is an important nosology, and doctors of both outpatient and hospital departments should be prepared for its early detection and diagnosis. The absence of specific symptoms and clear causes of onset, as well as the many associated clinical conditions, mean that knowledge of atrial fibrillation, especially its debut — the first diagnosed atrial fibrillation — is particularly necessary for general practitioners. This article analyzes literature on first diagnosed atrial fibrillation, focusing on the peculiarities of the disease’s course, diagnosis, choice of tactics, and treatment. The article introduces readers to information from modern publicly available publications on this topic, providing an overview of the key stages in the historical development of medicine in this area. Based on literary sources, existing problems of underestimating the danger of the disease, lack of unified approaches to patient management, and key definitions and concepts are revealed today.

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Cardioversion differences among first detected episode, paroxysmal, and persistent atrial fibrillation patients in the RHYTHM AF registry in Poland

Abstract: (Cardiol J 2015; 22, 4: 453-458)

Cited by 4 publications

References 15 publications

Antazoline for termination of atrial fibrillation during the procedure of pulmonary veins isolation

Antazoline for termination of atrial fibrillation during the procedure of pulmonary veins isolation

Recurrent event survival analysis predicts future risk of hospitalization in patients with paroxysmal and persistent atrial fibrillation

Features of diagnosis and treatment of newly diagnosed atrial fibrillation

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