Caregiver and Clinician Assessment of Behavioral Disturbances: The California Dementia Behavior Questionnaire

Victoroff, Jeff; Nielson, Kristy A.; Mungas, Dan M

doi:10.1017/s1041610297004316

Cited by 12 publications

(20 citation statements)

References 25 publications

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“…A modified version of the Alzheimer’s Disease Diagnostic and Treatment Centers (ADDTC) California Dementia Behavior Questionnaire (CDBQ) (Victoroff, Nielson, & Mungas, 1997) was used to evaluate patient behaviors. The questionnaire asks about the presence of behaviors in the last six months and the frequency of behaviors within the last one month.…”

Section: Methodsmentioning

confidence: 99%

Gender differences in sexual behaviors of AD patients and their relationship to spousal caregiver well-being

Davies

Sridhar

Newkirk

et al. 2011

Aging & Mental Health

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Objectives Little is known about gender differences in sexuality among community-dwelling heterosexual couples in which one partner has Alzheimer’s disease (AD). Few studies have examined gender differences in specific sexual behaviors or their associations with caregiver well-being. This study evaluated the impact of gender differences on intimacy and sexual satisfaction in marital relationships in which one partner has AD. Method Baseline measures were collected from 162 AD patients and their partners enrolled in a multisite study between 2001 and 2009 to evaluate gender differences in measures of intimacy, caregiver well-being, and patient sexual behaviors. Results While over 70% of all patients initiated physically intimate activities (i.e. kissing, hugging, and intercourse), most did not initiate intercourse specifically. Female caregivers reported higher levels of stress and depressive symptoms than male caregivers (p < .01). Satisfaction with intimacy was significantly associated with fewer stress and depressive symptoms in female caregivers (r = −.29, p < .01). Caregiver gender, satisfaction with intimacy, and caring for a patient with Mild AD were significant predictors of caregiver depressive symptoms (ps < .05). Conclusion The majority of couples dealing with AD reported engaging in intimacy, suggesting its importance in the relationship. Female caregivers who reported less sexual satisfaction reported more frequent stress and depressive symptoms. Caregiver gender, satisfaction with intimacy, and the AD patient’s level of cognitive functioning significantly contributed to caregiver well-being. Gender-specific therapies to address patient sexual difficulties and caregiver well-being could potentially maintain or improve the marital relationship.

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Section: Methodsmentioning

confidence: 99%

Gender differences in sexual behaviors of AD patients and their relationship to spousal caregiver well-being

Davies

Sridhar

Newkirk

et al. 2011

Aging & Mental Health

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“…Central training on uniform administration of the MUDS was provided as part of the Alzheimer's Disease Centers Program (35). Symptom ratings were made separately for depressed mood, apathy, anhedonia, and anergia as follows: 0=not present; 1=questionable; 2=present but mild at subthreshold or subsyndromal level; 3=present and severe at threshold or syndromal level; and 4=not determined.…”

Section: Methodsmentioning

confidence: 99%

Association of Depressed Mood and Mortality in Older Adults With and Without Cognitive Impairment in a Prospective Naturalistic Study

Lavretsky¹,

Zheng²,

Weiner³

et al. 2010

AJP

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Objective: The authors examined predictors of mortality in individuals age 50 or older with or without cognitive impairment in a 12-year prospective naturalistic study of subcortical ischemic vascular disease focusing on symptoms of depressed mood, apathy, anhedonia, or anergia. Method: A total of 498 participants were recruited from the community and from memory clinics into a multicenter longitudinal study of subcortical ischemic vascular disease. For baseline cognitive status, 36% of participants were assessed as cognitively intact, 31% as cognitively impaired, and 33% as demented. All participants underwent a research protocol MRI, and 41% were classified as having subcortical lacunes. Depressed mood, anhedonia, anergia, and apathy were assessed at baseline using a structured behavioral assessment. Cox regression models were used to investigate the associations between neuropsychiatric symptoms and mortality, controlling for age, gender, race, education level, cognitive status, presence of vascular lacunes, and vascular risk factors. Results: Of 498 participants, 175 (35%) died over the follow-up period, with a median survival time of 5.6 years. In the multivariate analyses, cognitive impairment, age, male gender, depressed mood, and the presence of lacunes predicted higher mortality. Participants with both lacunes and depressed mood had the shortest survival among all cognitive groups. The mortality hazard ratio for participants with depressed mood was 2.2 (95% CI=1.5–3.2) after adjustment for cognitive status, age, gender, education level, race, lacunes, and all vascular conditions. Conclusions: These findings suggest the importance of detecting depressed mood in individuals with cerebrovascular disease and of developing more aggressive treatment and preventive interventions for this vulnerable population.

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“…Central training on uniform administration of the MUDS was provided as part of the Alzheimer's Disease Centers Program (Victoroff et al , 1997). Symptom ratings were made separately for depressed mood, apathy, anhedonia or anergia based on severity, as follows: 0 = not present, 1 = questionable; 2 = present, but mild at subthreshold/subsyndromal level; 3 = present and severe at threshold/syndromal level; or 4 = not determined.…”

Section: Methodsmentioning

confidence: 99%

“…The assessment of each of these neuropsychiatric behaviors was based on the patient and caregiver report, and direct clinical examination. Victoroff and colleagues (1997) determined the reliability of caregiver ratings and compared caregiver ratings with clinician ratings of all types of behavioral disturbances. Caregiver and clinical inter-rater reliability was highest for depression and lowest for psychosis ranging between r 0.2 and 0.9.…”

Section: Methodsmentioning

confidence: 99%

The MRI brain correlates of depressed mood, anhedonia, apathy, and anergia in older adults with and without cognitive impairment or dementia

Lavretsky

Zheng

Weiner

et al. 2008

Int J Geriat Psychiatry

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SUMMARY Objectives We examined the magnetic resonance imaging (MRI) correlates of depressed mood, apathy, anhedonia, and anergia in older adults with and without cognitive impairment or dementia. Methods This analysis included 270 community-dwelling older adults (59% male; 79% Caucasian; mean age 74.4 years) who were recruited into a multi-center longitudinal observational study of subcortical ischemic vascular disease (SIVD).The distribution of cognitive status included: cognitively intact (38%), cognitively impaired (27%), or demented (35%). All subjects underwent MRI and 41% were classified as having subcortical lacunes. MRI measures included cortical gray and white matter volumes, lacunar volumes in subcortical white and gray matter structures, volume of white matter hyperintensities, and total hippocampal volume. Depressed mood, anhedonia, anergia, and apathy apparent at the time of assessment were assessed using a behavioral assessment Associations between neuropsychiatric symptoms and MRI variables were evaluated using logistic regression. Results Subjects with neuropsychiatric symptoms were more likely to be cognitively impaired or demented than those without neuropsychiatric symptoms. In multivariate models controlling for cognitive status, age, gender, and education, higher lacunar volume in white matter was independently associated with the presence of all four neuropsychiatric symptoms. Conclusions We report an association between the lacunar volumes in the white matter and depressed mood, anhedonia, apathy, and anergia, thus supporting the role of subcortical ischemic vascular disease in the pathogenesis of late-life neuropsychiatric disorders.

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Caregiver and Clinician Assessment of Behavioral Disturbances: The California Dementia Behavior Questionnaire

Cited by 12 publications

References 25 publications

Gender differences in sexual behaviors of AD patients and their relationship to spousal caregiver well-being

Gender differences in sexual behaviors of AD patients and their relationship to spousal caregiver well-being

Association of Depressed Mood and Mortality in Older Adults With and Without Cognitive Impairment in a Prospective Naturalistic Study

The MRI brain correlates of depressed mood, anhedonia, apathy, and anergia in older adults with and without cognitive impairment or dementia

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