Though much research links socioeconomic disadvantage to cognitive difficulties, many youth demonstrate resilience. Person-centered approaches can be used to quantify this developmental heterogeneity and challenge deficit-centered frameworks. This study leverages person-centered and data-driven methods to quantify and characterize cognitive heterogeneity in early adolescents experiencing socioeconomic disadvantage. In a sample of 9,839 youth from the Adolescent Brain Cognitive Development℠ Study (47.7% female sex; Mage=9.90 years; 46.7% White), four profiles based on SER and multi-domain cognitive functioning were identified, including two profiles characterized by moderate-to-high-SER (74.5%) and two profiles characterized by low-SER (25.5%). Among youth in low-SER environments, 88.6% were classified as Cognitively Resilient and 11.4% were classified as Cognitively Vulnerable. Despite having the least SER, youth in the Cognitive Resilience profile demonstrated cognitive performance scores similar to youth with moderate-to-high access to SER. In contrast, youth in the Cognitive Vulnerability profile demonstrated markedly lower performance compared to the other profiles (i.e., 1.3 to 2.3 SD below the sample mean). Ridge regression identified predictors of profile membership at the individual level and within family, neighborhood, and school environments. Suburban residence (OR=1.31), advanced pubertal maturity (OR=1.20), bilingualism (OR=1.14), and greater caregiver monitoring (OR=1.10) were most strongly associated with lower-SER youths’ membership in the Cognitive Resilience profile. Results emphasize the need to challenge deficit-centered frameworks by investigating heterogeneity within adversity-exposed youth and identifying context-specific risk and protective factors. NOTE: This paper is currently under review (submitted 6/3/2024).