Caregiver's acceptability of zinc tablet for treatment of childhood diarrhea in rural and urban communities

Jalo, Ibrahim Rabiu; Jibo, Abubakar Mohammed; Gajida, AU; Kwaku, AA; Awaisu, N; Yusuf, AM; Kauranmata, AI; Yusuf, S. R.; Shuaibu, SY; Musa, Abuhuraira Ado; Abubakar, IS

doi:10.4103/smj.smj_61_18

Cited by 1 publication

(2 citation statements)

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“…13 Acceptability of zinc tablet among caregivers was found to be optimal as up to 81.1% of the caregivers in both rural and urban settings were found to have good acceptability. 14 In Kenya, evaluation of acceptability and knowledge of zinc-use to treat diarrhoea showed 79.5% of caregivers had good acceptability. 15 A systematic study reveals that vomiting after zinc intake is common in all age groups.…”

Section: Discussionmentioning

confidence: 99%

“…In this study, parents/caregivers were instructed by a trained physician, so more comprehensive information could be imparted successfully which might be the explanation of high acceptance of zinc as a treatment that may not have been followed in previous study 13 . Acceptability of zinc tablet among caregivers was found to be optimal as up to 81.1% of the caregivers in both rural and urban settings were found to have good acceptability 14 . In Kenya, evaluation of acceptability and knowledge of zinc‐use to treat diarrhoea showed 79.5% of caregivers had good acceptability 15 …”

Section: Discussionmentioning

confidence: 99%

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New formulation zinc sulphate acceptability and adherence in children with acute diarrhoea: A prospective, open‐label, interventional study in Bangladesh

Nuzhat

Ahmed

Alam

et al. 2022

J Paediatrics Child Health

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Aim: Zinc is an adjunct to oral rehydration salts for management of diarrhoea in children. Due to zinc's unpleasant taste, children often develop nausea and/or vomiting. We aimed to assess acceptability (tolerability) and adherence of improvised formulation of zinc tablet among under-five children with acute diarrhoea. Methods: This was an open-label intervention trial among 3-59 months old diarrhoeal children attending the outpatient department of Dhaka Hospital, who were enrolled in two age strata, 3 to <18 months and 18-59 months. Zinc tablets 10 or 20 mg per day were prescribed for a total of 10 days for <6 months and ≥6 months age children respectively, with follow-up. Diary-cards were used to record events. Results: In stratum 1, 158 (90.8%) children and in stratum 2, 144 (95.4%) children completed the study as per protocol out of 325 enrolled children. Sociodemographic, clinical and anthropometric measurements were comparable in the two strata except admission diarrhoeal duration (median 3 days vs. 2 days, P = 0.001). Adherence to 10 days treatment was 123 (77.8%) in stratum 1 and 127 (88.2%) in stratum 2. Zinc tablets were tolerated very well/well in 280 (92.7%) children. Vomiting, regurgitation and nausea were observed in 99 (32.8%), 59 (19.5%) and 22 (7.4%) children respectively. Caregivers' willingness to use the same drug in future was 300 (99.3%) among all children. Conclusion: Our study findings demonstrate that modified taste and formulation zinc tablets were well tolerated, and caregivers' willingness to use this formulation in future supports its acceptability, adherence and palatability.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%