The relevance of ensuring energy efficiency and environmental compatibility in all sectors of the economy is growing every year. Transport is one of the key factors in the successful development of the global economy, which ensures, among other things, the continuous movement of goods to support global value chains. The methodological basis of the study is represented by the provisions of modern economic theory, logistics, transport systems, management, ecology, and energy efficiency. A number of general scientific and special methods were used to solve the tasks, in particular, methods of formalisation, system and statistical analysis, probability theory, typology, abstract and logical synthesis. As part of the study, an effective mechanism for ensuring energy efficiency and environmental compatibility in the delivery of special categories of cargo was proposed which can be used to most effectively solve the tasks set throughout the supply chain. The proposed mechanism is formed by environmental and energy-efficient tools, a support system, internal and external contradictions to achieve an environmental and energy balance. The toolkit is fully consistent with the public interest, as well as with the goals of Industry 5.0 in ensuring the environmental effect as part of the path to a circular economy, increasing the reliability and sustainability of value chains through the formation of increased responsibility of participants in the process of delivering special cargo, as well as the implementation of the principles of environmental and social management.