Caring for the Elderly Cancer Patient: Training the Next Generation of Oncologists

Lyman, Gary H.

doi:10.1200/jop.0841503

Cited by 2 publications

(1 citation statement)

References 12 publications

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“…Fortunately, there are clinical trials within various cooperative groups directed toward the development of effective and safe treatment strategies for the older people with cancer. These considerations will have important implications for training the next generation of healthcare professionals to meet the future needs [ 57 ] of older people living with cancer.…”

Section: Summary and Outlook For The Futurementioning

confidence: 99%

Clinical Pharmacology of Chemotherapy Agents in Older People with Cancer

Clarke

McLachlan

2011

Current Gerontology and Geriatrics Research

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Populations around the world are aging, and the associated increase in cancer incidence has led to the recognition of the importance of geriatric oncology. Chronological age is a poor determinant of pharmacological response to cancer chemotherapy agents. Age-associated changes in physiology and organ function have a significant impact on the clinical pharmacology of cancer chemotherapy agents used in cancer treatment. Altered response to medicines in older people is a consequence of changes in body composition, organ function, concomitant pathophysiology, multiple medications, genetic determinants of drug response, and patient's clinical status. These issues highlight the need to individualize the management of cancer in the older people with consideration of age-related changes in the clinical pharmacology of cancer drugs, analgesics, and adjunctive therapies.

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Section: Summary and Outlook For The Futurementioning

confidence: 99%

Clinical Pharmacology of Chemotherapy Agents in Older People with Cancer

Clarke

McLachlan

2011

Current Gerontology and Geriatrics Research

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Workforce characteristics and interventions associated with high-quality care and support to older people with cancer: a systematic review

et al. 2017

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ObjectivesTo provide an overview of the evidence base on the effectiveness of workforce interventions for improving the outcomes for older people with cancer, as well as analysing key features of the workforce associated with those improvements.DesignSystematic review.MethodsRelevant databases were searched for primary research, published in English, reporting on older people and cancer and the outcomes of interventions to improve workforce knowledge, attitudes or skills; involving a change in workforce composition and/or skill mix; and/or requiring significant workforce reconfiguration or new roles. Studies were also sought on associations between the composition and characteristics of the cancer care workforce and older people's outcomes. A narrative synthesis was conducted and supported by tabulation of key study data.ResultsStudies (n=24) included 4555 patients aged 60+ from targeted cancer screening to end of life care. Interventions were diverse and two-thirds of the studies were assessed as low quality. Only two studies directly targeted workforce knowledge and skills and only two studies addressed the nature of workforce features related to improved outcomes. Interventions focused on discrete groups of older people with specific needs offering guidance or psychological support were more effective than those broadly targeting survival outcomes. Advanced Practice Nursing roles, voluntary support roles and the involvement of geriatric teams provided some evidence of effectiveness.ConclusionsAn array of workforce interventions focus on improving outcomes for older people with cancer but these are diverse and thinly spread across the cancer journey. Higher quality and larger scale research that focuses on workforce features is now needed to guide developments in this field, and review findings indicate that interventions targeted at specific subgroups of older people with complex needs, and that involve input from advanced practice nurses, geriatric teams and trained volunteers appear most promising.

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Caring for the Elderly Cancer Patient: Training the Next Generation of Oncologists

Cited by 2 publications

References 12 publications

Clinical Pharmacology of Chemotherapy Agents in Older People with Cancer

Clinical Pharmacology of Chemotherapy Agents in Older People with Cancer

Workforce characteristics and interventions associated with high-quality care and support to older people with cancer: a systematic review

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