A collection of illnesses or injuries affecting the nerves, muscles, tendons, bones, joints, cartilage, and intervertebral discs are referred to as musculoskeletal disorders (MSDs). Dentists are more likely to develop work-related MSDs, which can result in unsuitable positions during work for extended periods, repetitive, unnatural motions, genetic predisposition, aging, and mental pressure. Common MSDs include tension neck syndrome, cervical radiculopathy, back pain syndrome, and carpel tunnel syndrome. More than one-third of dentists seek medical assistance for these MSDs, which have an impact on their daily and professional lives. Therefore, the present review article aims to address and discuss the common musculoskeletal hazards faced by dental professionals and emphasizes the importance of a holistic approach and effective strategies for prevention and promoting the well-being of dental professionals.