Carnitine administration to sea bass (Dicentrarchus labrax (L.)) during feeding on a fat diet: Modification of plasma lipid levels and lipoprotein pattern

Santulli, Andrea; Modica, Aurora; Curatolo, A; D’Amelio, V.

doi:10.1016/0044-8486(88)90248-7

Cited by 32 publications

(20 citation statements)

References 9 publications

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“…However, Santulli et al (1988) observed that carnitine feeding reduced the level of total cholesterol in plasma. The supplementation of Cr-Pic increased serum total protein whereas it decreased cholesterol concentrations in chickens, rats and calves (Anderson 1987;Mertz 1993).…”

Section: Discussionmentioning

confidence: 84%

Effects of dietary l-carnitine and chromium picolinate supplementations on performance and some serum parameters in rainbow trout (Oncorhynchus mykiss)

et al. 2008

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An experiment was conducted to determine the effects of supplemental dietary L-carnitine, chromium picolinate (Cr-Pic) and their combination on growth performance and serum total protein, cholesterol, triglyceride and glucose of rainbow trout (Oncorhynchus mykiss). A total of 276 rainbow trout were randomly allocated to four groups. Fish (average initial body weight = 151 ± 1.69 g) were fed a basal diet without supplemental L-carnitine and chromium picolinate in the control group. The basal diet was supplemented with either 500 mg/kg L-carnitine, 1.6 mg/kg chromium picolinate or 500 mg/kg L-carnitine plus 1.6 mg/kg chromium picolinate for experimental groups 1 (C), 2 (Cr-Pic) and 3 (C ? Cr-Pic), respectively. Fish were fed twice a day to apparent satiation for 58 days. Weight gain, growth rate, feed consumption and feed conversion ratio (feed/ gain) were calculated for the whole period. At the end of the study, six fish were chosen randomly from each tank to represent the experiment and frozen at -20°C for subsequent dorsal muscle analysis. The results showed no significant differences in final body weight, weight gain or feed conversion ratio among groups. There were also no significant differences in serum total protein, cholesterol, triglyceride or glucose concentrations among groups. Significantly higher lipid concentration of dorsal muscle was observed in experimental groups 1 and 3. In conclusion, supplemental dietary L-carnitine, chromium picolinate and their combination have no beneficial effects on improving growth performance and feed conversion ratio in rainbow trout. However, dietary L-carnitine slightly increased lipid concentration in dorsal muscle of rainbow trout.

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Section: Discussionmentioning

confidence: 84%

Effects of dietary l-carnitine and chromium picolinate supplementations on performance and some serum parameters in rainbow trout (Oncorhynchus mykiss)

et al. 2008

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“…In fish, these plasma lipid‐lowering effects of carnitine administration have also been found in European sea bass (Santulli et al . ). These studies indicate that the decrease in plasma levels of triacylglycerols, total cholesterol and free fatty acids was a result of carnitine feeding.…”

Section: Discussionmentioning

confidence: 97%

Effects of dietary L-carnitine level on growth performance, body composition and antioxidant status in beluga (Huso husoL. 1758)

Mohseni

Ozório

2014

Aquacult Nutr

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A 17‐week feeding trial was carried out to evaluate the effects of dietary L‐carnitine level in beluga, Huso huso. A total of fish averaging 1247 ± 15.6 g (mean ± SD) were randomly distributed into 18 fibreglass tanks, and each tank holding 10 fish was then randomly assigned to one of three replicates of six diets with 50, 150, 350, 650, 950 and 1250 mg L‐carnitine kg−1 diet. At the end of 17 weeks of feeding trial, average weight gain (WG), feed efficiency (FE), protein efficiency ratio (PER) and condition factor (CF) of fish fed 350 mg kg−1 diet were significantly (P < 0.05) higher than those of fish fed 50, 150, 950 and 1250 mg kg−1 diets. WG, FE, PER and CF of beluga fed 650 mg kg−1 diet were also significantly higher than those of fish fed 50, 950 and 1250 mg kg−1 diets. Whole body and muscle protein were significantly improved by the elevation of dietary L‐carnitine level up to 350 mg kg−1. Liver superoxide dismutase and glutathione peroxidase activities of fish fed 350 and 650 mg kg−1 diets were significantly higher than those of fish fed 50, 950 and 1250 mg kg−1 diets. The dietary L‐carnitine level of 350–650 mg kg−1 diet could improve growth performance, feed utilization, protein‐sparing effects of lipid, antioxidant defence system and reproductive success. Polynomial regression of WG suggested that the optimum dietary L‐carnitine level was 480 mg kg−1 diet. Therefore, these results may indicate that the optimum dietary L‐carnitine could be higher than 350 but <650 mg kg−1 diet in beluga reared in intensive culture conditions.

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“…0 (1.1) 0.0 (1.4) 0.0 (1.7) 0.1 (1.1) 0.1 (1.4) 0.1 (1.7) 3 1.54 (8.1) a 7.42 (0.33) 24.6 1 (4.22) a 29.65 (6.3) a 7.17 (0.22) 22.63 (2.38) abc 3 1.06 (5.1) Lipid reduction in dark muscle, liver, and visceral fat in this study may not occur when other diet formulas are used. When sea bass were fed high-fat diets, supplemented dietary carnitine between 100 and 250 mg/kg wet fish weight per day reduced plasma lipids, primarily triglycerides, presumably by carnitine effects on lipid metabolism (Santulli et al 1988). However, sea bass fed a standard diet, low in fat, without supplemented carnitine had plasma lipid concentrations similar or lower than sea bass fed high-fat diets and carnitine.…”

Section: Discussionmentioning

confidence: 99%

“…A protein sparing effect of carnitine was observed which could offset weight loss associated with fat reduction (Santulli et al 1988(Santulli et al , 1990. Information concerning carnitine effects in fish is very limited compared with other animals, and carnitine biosynthesis, metabolism and function are not well understood.…”

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confidence: 99%

Dietary Carnitine and Lysine Affect Channel Catfish Lipid and Protein Composition

Burtle

Liu

1994

J World Aquaculture Soc

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The effects of carnitine (L‐carnitine) at 0.1% were tested at three levels of dietary lysine (L‐lysine‐HCl), 1.1, 1.4 or 1.7%, with fingerling channel caffish. Semipurified diets containing 30% protein and 3.44 kcal digestible energy/g were fed for 8 wk in flow‐through water at 26.5 ± 0.5 C. Carnitine did not significantly (P > 0.71) affect channel catflsh weight gain over this time interval. Weight gain was less when 1.1% dietary lysine was fed without supplemented carnitine than when diets contained 1.4 or 1.7% lysine. Carnitine reduced muscle lipid (P < 0.0003) and liver lipid (P < 0.0001) significantly. Percentage visceral fat was reduced with added dietary carnitine (P < 0.0001) but not with dietary lysine although there was a combined effect of carnitine and lysine (P < 0.0008). Channel catfish wholebody lipid content was reduced by supplemented dietary carnitine, lysine, or both. Protein content of channel catfish wholebody increased with added carnitine, lysine, and their interaction (P < 0.19, P < 0.003 and P < 0.001). Under these conditions, dietary carnitine improves caffish tissue characteristics by reducing fat content and increasing protein content.

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Carnitine administration to sea bass (Dicentrarchus labrax (L.)) during feeding on a fat diet: Modification of plasma lipid levels and lipoprotein pattern

Cited by 32 publications

References 9 publications

Effects of dietary l-carnitine and chromium picolinate supplementations on performance and some serum parameters in rainbow trout (Oncorhynchus mykiss)

Effects of dietary l-carnitine and chromium picolinate supplementations on performance and some serum parameters in rainbow trout (Oncorhynchus mykiss)

Effects of dietary L-carnitine level on growth performance, body composition and antioxidant status in beluga (Huso husoL. 1758)

Dietary Carnitine and Lysine Affect Channel Catfish Lipid and Protein Composition

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