Caroli's Disease: Report of Surgical Options and Long-Term Outcome of Patients Treated in Argentina. Multicenter Study

Lendoire, Javier; Raffin, G.; Grondona, J.; Bracco, Ricardo; Russi, Rodolfo; Ardiles, Victoria; Gondolesi, Gabriel; Defelitto, Jorge; Santibañés, Eduardo de; Imventarza, Oscar

doi:10.1007/s11605-011-1620-9

Cited by 23 publications

(19 citation statements)

References 28 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The latter is a combination of cystic bile duct disease with congenital hepatic fibrosis [46]. Several studies with up to 33 patients with Caroli's disease suggest that there is an increased incidence of CCA in patients with Caroli's disease [47,48,49]. …”

Section: Biliary Disordersmentioning

confidence: 99%

Epidemiology and Risk Factors of Cholangiocarcinoma

Kirstein

Vogel²

2016

Visc Med

151

127

View full text Add to dashboard Cite

Background: Cholangiocarcinoma (CCA) is the second most common primary liver cancer, being characterized by its late diagnosis and fatal outcome. Recent epidemiological reports indicate an increasing worldwide incidence of intrahepatic CCA but a decreasing incidence of extrahepatic CCA. Methods: In this review, we present an overview of the incidence and epidemiology of CCA and possible strategies for screening and surveillance. Results: Efficient strategies for the screening and surveillance of CCA have not been established so far. The vast majority of CCA occur sporadically without any apparent cause; however, several risk factors such as liver flukes, chronic biliary and liver diseases, and lifestyle-related aspects causing chronic inflammation and cholestasis in the liver have been linked to the development of CCA. These risk factors likely contribute to the increased incidence observed in some countries and also explain the wide geographical differences in the incidence of CCA. Conclusion: Several risk factors for CCA have been identified. Given the dismal prognosis of advanced CCA, regular surveillance examinations with a combination of ultrasonography and laboratory tests appear to be useful in patients at risk and need to be explored in prospective trials.

show abstract

Section: Biliary Disordersmentioning

confidence: 99%

Epidemiology and Risk Factors of Cholangiocarcinoma

Kirstein

Vogel²

2016

Visc Med

151

127

View full text Add to dashboard Cite

show abstract

“…72,138 Asymptomatic bilobar disease is typically managed nonoperatively, at which point aggressive surveillance for potential malignant transformation is warranted. 139,140 Although prophylactic OLT is not indicated, complicated bilobar Caroli's disease with cholangitis, portal hypertension, or suspicion of early malignant transformation is definitively best managed with OLT. 72,139,141-143 Both liver resection and OLT produce excellent and comparable long-term outcomes and survival rates.…”

Section: Managementmentioning

confidence: 99%

“…139,140 Although prophylactic OLT is not indicated, complicated bilobar Caroli's disease with cholangitis, portal hypertension, or suspicion of early malignant transformation is definitively best managed with OLT. 72,139,141-143 Both liver resection and OLT produce excellent and comparable long-term outcomes and survival rates. 72,138,140,141,143,144 …”

Section: Managementmentioning

confidence: 99%

Choledochal Cysts: Presentation, Clinical Differentiation, and Management

Soares

Arnaoutakis

Kamel

et al. 2014

Journal of the American College of Surgeons

244

285

View full text Add to dashboard Cite

“…[16] Bilateral disease is more difficult to manage. Initially, an attempt can be made to clear the hepatolithiasis burden with endoscopic and/or percutaneous lithectomy, but these techniques often fail as the disease progresses.…”

Section: Treatment Of Cystic Lesionsmentioning

confidence: 99%

SSAT/AHPBA Joint Symposium on Evaluation and Treatment of Benign Liver Lesions

Chun

House

Kaur

et al. 2013

Journal of Gastrointestinal Surgery

View full text Add to dashboard Cite

Background Benign liver lesions are common incidental radiologic findings. Methods Experts convened in 2011 at a Society for Surgery of the Alimentary Tract/ Americas Hepato-Pancreato-Biliary Association joint symposium to discuss the evaluation and treatment of benign liver lesions. Results Most benign liver lesions can be accurately diagnosed with high-quality imaging, including ultrasonography, multiphase computed tomography, and magnetic resonance imaging, particularly with hepatocyte-specific contrast agents. Percutaneous biopsy is reserved for lesions that cannot be characterized radiographically, and its accuracy is improved with immunophenotypic markers. Hepatic cysts are the most commonly diagnosed benign liver lesions; these must be distinguished from malignant cystic lesions, which are rare. Among the solid benign liver lesions, hemangiomas and focal nodular hyperplasia seldom require treatment. In contrast, hepatocellular adenomas are associated with a risk for complications. A new classification system for hepatocellular adenomas based on genetic and phenotypic features can help guide patient care. In patients who are symptomatic or at risk for complications, multidisciplinary evaluation and treatment based on clinicopathologic, radiographic, and molecular analysis is needed. Conclusions Most benign liver lesions can be accurately diagnosed radiographically and do not require treatment. Treatment is necessary for patients with symptoms or at risk for complications.

show abstract

Caroli's Disease: Report of Surgical Options and Long-Term Outcome of Patients Treated in Argentina. Multicenter Study

Cited by 23 publications

References 28 publications

Epidemiology and Risk Factors of Cholangiocarcinoma

Epidemiology and Risk Factors of Cholangiocarcinoma

Choledochal Cysts: Presentation, Clinical Differentiation, and Management

SSAT/AHPBA Joint Symposium on Evaluation and Treatment of Benign Liver Lesions

Contact Info

Product

Resources

About