Carotid Artery Disease - Left vs Right

Ionescu, Ana-Maria; Carciumaru, Nicolae; Chirila, Sergiu

doi:10.1515/arsm-2016-0028

Cited by 4 publications

(2 citation statements)

References 6 publications

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“…[37] Wall shear stress, generated by blood viscosity and blood flow velocity, makes arteries prone to atherosclerotic plaque development when they are low, especially in the carotid arteries of individuals at risk, increasing the incidence of stroke. [37][38][39] The hemodynamic disturbance at the carotid bifurcation increases endothelial cell damage, transient reversal of flow and separation with eddy formation, resulting in atherosclerotic plaques at the bulb. [38,40] Plaques at the bulb are a better predictor of coronary artery disease than those at the CCA.…”

Section: Discussionmentioning

confidence: 99%

Carotid Doppler Ultrasonography in Patients with Co-existing Type 2 Diabetes Mellitus and Hypertension in Nigeria

Adekoya¹,

Olatunji²,

Akinola³

et al. 2022

Ann Health Res

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Background: The co-existence of diabetes mellitus (DM) and hypertension (HTN) has been rising globally with subclinical atherosclerotic complications. These vascular changes can be detected using carotid ultrasonography. Objectives: To determine and compare the carotid arterial structural wall changes and blood flow velocities of adults with co-existing DM and HTN with age- and sex-matched non-diabetic, non-hypertensive controls. Methods: A cross-sectional comparative study of 300 participants comprising 200 adults with co-existing DM and HTN and 100 age- and sex-matched controls was done. Their carotid arteries were examined bilaterally for plaques, carotid intima media thickness (CIMT) and flow velocities – peak systolic velocity (PSV), end diastolic velocity (EDV), pulsatility index (PI) and resistive index (RI) using 4–12MHz linear array transducer. Visceral obesity and serum lipids were also assessed. Results: The mean age of the subjects was 56.13 ± 6.93 years; they comprised 38% males and 62% females. The subjects’ CIMT was statistically significantly higher (p = 0.001) with a three-fold mean increase (45.5%) compared to the controls (13.7%). Lower flow velocities but higher indices were also observed in the subjects. Strong and significant correlations were observed between EDV and PI (r =-0.663, p =>0.001), EDV and RI (r = -0.661, p =>0.001) and PI and RI (r =0.988, p = >0.001) among the subjects. Conclusion: Significant reduction in flow velocities with increased CIMT may be an early indication of subclinical atherosclerosis. Therefore, carotid ultrasonography should be mandatory in individuals at risk for early detection and possible prevention of atherosclerotic complications.

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Section: Discussionmentioning

confidence: 99%

Carotid Doppler Ultrasonography in Patients with Co-existing Type 2 Diabetes Mellitus and Hypertension in Nigeria

Adekoya¹,

Olatunji²,

Akinola³

et al. 2022

Ann Health Res

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“…Different arterial pressure in the right and left eyes are possible because the right retinal artery is a branch of the right internal carotid artery to the brachiocephalic artery then aorta while the left retinal artery is a branch of the left internal carotid artery which originates directly from the aorta which make the left carotid artery may got exposed to a higher arterial pressure. [11][12][13] However, this findings raised several questions regarding the underlying mechanisms in each eye.…”

Section: Introductionmentioning

confidence: 96%

Interleukin-1A May Illuminate Differential Effects of the Retinal Artery Caliber in HIV Patients

Edwar

Ariyanto

Tanudjaja

et al. 2021

Mol Cell Biomed Sci

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Background: Retinal artery caliber (RAC) is narrower in human immunodeficiency virus (HIV)-infected patients beginning antiretroviral therapy (ART). We aimed to assess associations between variations in genes encoding inflammatory mediators and natural killer receptors and retinal artery caliber (RAC) in HIV patients beginning ART.Materials and Methods: Seventy-nine HIV positive patients beginning ART with less than 200 cluster of differentiation (CD) 4 T-cells/μL were recruited. Examinations were performed before ART (V0) and at months 3, 6 and 12 (V3, V6, V12). The study was approved by ethics committees and informed consent was obtained from each subject.Results: Right and left RAC of the HIV patients were narrower than healthy controls (p=0.016 for right RAC) and narrowed further on ART, but demographic associations with the right and left RAC were not identical. Here we show that polymorphisms in genes encoding NK receptors or TNF activity had no significant impact, but right RAC was associated with carriage of allele 2 at IL1A+4845 (p=0.037 after 12 months on ART).Conclusion: Overall the paradoxical reduction in the RAC in HIV patients responding to ART was not modified by genotypes known to affect NK cell function or TNF responses, but IL1A genotype may modify the decline in the right RAC.Keywords: anti-retroviral therapy, CMV, HIV, IL1A, retinal artery caliber

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Carotid angle in young stroke

Apaydin¹,

Cetinoglu

2021

Clinical Imaging

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Carotid Artery Disease - Left vs Right

Cited by 4 publications

References 6 publications

Carotid Doppler Ultrasonography in Patients with Co-existing Type 2 Diabetes Mellitus and Hypertension in Nigeria

Carotid Doppler Ultrasonography in Patients with Co-existing Type 2 Diabetes Mellitus and Hypertension in Nigeria

Interleukin-1A May Illuminate Differential Effects of the Retinal Artery Caliber in HIV Patients

Carotid angle in young stroke

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