“…The data in that analysis did not support LSA revascularization for stroke prevention, and other large data sets, including the National Surgical Quality Improvement Program registry, 170 and prior meta-analyses [171][172][173] have found no benefit with regard to stroke prevention for LSA revascularization in patients undergoing zone 2 TEVAR, perhaps because strokes during zone 2 TEVAR are generally embolic in nature. 174 Currently available techniques for LSA revascularization in conjunction with TEVAR include surgical carotidsubclavian bypass, 175 carotid-subclavian transposition, 176 and carotid-axillary bypass, 177 along with endovascular techniques, including chimney grafts, scallops, fenestrated grafts, and branched grafts. 178 Surgical revascularization techniques are associated with not insignificant risks of phrenic and recurrent laryngeal nerve palsy, 175 although these risks may be decreased with carotid-axillary bypass 177 due to avoidance of any manipulation in the vicinity of the phrenic nerve.…”