Carotid body paraganglioma: review and surgical management

Dimakakos, P; Kotsis, Thomas

doi:10.1007/s002380100231

Cited by 30 publications

(44 citation statements)

References 33 publications

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“…Horner's syndrome due to invasion or compression of cervical sympathetic chain, and syncope may be seen due to carotid sinus or internal carotid artery compression as the size of the tumor also matters in management [17]. Cranial nerve palsies are seen in 30 % of the cases with vagus being the commonest [18]. Catecholamine production may manifest as fluctuating hypertension, blushing, obstructive sleep apnea and palpitations [4][5][6].…”

Section: Discussionmentioning

confidence: 99%

“…Malignant transformation is seen in 10 %, familial in 10 %, and bilateral in 10 % of sporadic cases where bilaterality may reach 30 % in the familial cases [18,28].…”

Section: Discussionmentioning

confidence: 99%

“…Scudder in 1903 demonstrated first successful removal of carotid body paraganglioma later in 1940 Gordon-Taylor described a safe subadvential plane of tumor dissection [39]. Mortality was 50-60 % and 15-30 % of patients suffered stroke before the advent of current vascular surgical techniques as larger tumors invariably needed common carotid artery ligation [18]. Surgical resection is the only treatment of choice for CBP, though preoperative chemoembolization and radiation therapy have been used in some centers [40].…”

Section: Discussionmentioning

confidence: 99%

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Paragangliomas of the Carotid Body: Current Management Protocols and Review of Literature

Naik

Shenoy

Nanjundappa

et al. 2013

Indian J Surg Oncol

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Paraganglioma is a rare neoplasm arising from carotid body usually benign and constitute 0.5 % of all total body tumors. They constitute 60-70 % of head and neck paraganglioma and resemble other paragangliomas of the body like glomus jugulare, glomus tympanicum, and pheochromocytoma. This is a retrospective analysis of the medical records of carotid body paraganglioma cases. Nine patients operated during the study period and the follow up traced were included in the study. Seven females and 2 males were analysed. Six had tumor on the left side and 3 had on the right side. All the cases surgical excision was done by a tranverse incision as 2 patients had Shamblin I, 5 patients had Shamblin II, and 1 patients Shamblin IIIa. All the Shamblin I had tumor away from the carotids and were easily dissected without vessel damage, a sub adventitial tumor excision was performed in all the 5 cases of Shamblin II, 1 case of Shamblin IIIa was dissected with difficulty without sacrificing or vessel reconstruction. Paraganglioma of the carotid body should be considered as a differential diagnosis for painless lateral neck masses. Larger tumors need a multidisciplinary team of head and neck with vascular surgeons for better results.

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Section: Discussionmentioning

confidence: 99%

“…Malignant transformation is seen in 10 %, familial in 10 %, and bilateral in 10 % of sporadic cases where bilaterality may reach 30 % in the familial cases [18,28].…”

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Paragangliomas of the Carotid Body: Current Management Protocols and Review of Literature

Naik

Shenoy

Nanjundappa

et al. 2013

Indian J Surg Oncol

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“…7 Carotid body paraganglioma was reported to be malignant in 10%, familial in 10%, and bilateral in 10% of sporadic cases, bilaterality may reach 30% in the familial cases. 4,8 Metastatic malignant CBP occurs in 5% of cases, and usually metastasis confined to the neck. Multicentricity of paragangliomas can occur in up to 25% of patients.…”

Section: Discussionmentioning

confidence: 99%

Carotid body tumour-- A rare case report

Sharma¹,

Chaudhary²,

Aneja³

2012

IOSR-JDMS

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“…Carotid paraganglia are composed of chemoreceptor cells derived from the carotid primitive neural crest. 1,4 In general, tumors arising from any paraganglionic tissue are best called paragangliomas (PGLs) and are arbitrarily classified by their relationship to the adrenal gland (adrenal medullary tumors or pheochromocytomas and extra-adrenal PGLs). Carotid body tumour is the most common form of paraganglioma of the head and neck region 5 .…”

Section: Introductionmentioning

confidence: 99%

Carotid Body Tumor – A Case Report

C.S¹,

B.M²,

M³

et al. 2013

jemds

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Carotid body tumors are rare neoplasms, which typically present as a slow growing, painless neck mass found along the anterior border of the sternocleidomastoid muscle. All borders were well-defined. It was non pulsatile, had no cranial nerve involvement. Neck glands were not enlarged. Her haematological and biochemical investigations did not reveal any abnormality. These tumors are generally benign but possess aggressive local growth potential. A 50 year female patient presented with a large (70 × 50 × 45 mm) sized swelling on the left side of the neck in the anterior triangle. CT with contrast revealed a hyper vascular lesion 5x4 cm at the carotid fork and not attached to the vessel (Shamblin type II).The operation was performed under general anaesthesia with endotracheal intubation. There were a lot of feeding vessels between the tumour mass and external and common carotid artery. The tumour was excised along the subadventitial plane. Histological examination of the tumor mass was done and it revealed typical features of nonsecreting paraganglioma. The patient recovered well from the effect of anaesthesia and there were no neurological deficit. Therefore, definitive treatment requires surgical resection. Paragangliomas (PGLs) are extra-adrenally located in 10% of cases. The authors describe a case of a patient with a carotid body tumor and review the most recent literature on this unusual topic.

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Carotid body paraganglioma: review and surgical management

Cited by 30 publications

References 33 publications

Paragangliomas of the Carotid Body: Current Management Protocols and Review of Literature

Paragangliomas of the Carotid Body: Current Management Protocols and Review of Literature

Carotid body tumour-- A rare case report

Carotid Body Tumor – A Case Report

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