Carotid body tumors: A report of three cases and current literature review

Müdüroğlu, Ayhan; Yuksel, Ahmet

doi:10.15761/vdt.1000136

Cited by 8 publications

(14 citation statements)

References 10 publications

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“…Comparatively, complications of HNPG after radiation therapy appeared to be much better tolerated and we observed a 100% control rate (arrest of growth) with radiotherapy in our series. Several groups have also indicated excellent local tumor control, with rates between 85% and 100% 24‐31 . Moreover, of the 20 patients that were initially observed, 70% remained stable over the years or with minimal growth, and only 30% needed further active treatment due to rapid growth or clinically significant symptoms.…”

Section: Discussionmentioning

confidence: 99%

“…Several groups have also indicated excellent local tumor control, with rates between 85% and 100%. [24][25][26][27][28][29][30][31] Moreover, of the 20 patients that were initially observed, 70% remained stable over the years or with minimal growth, and only 30% needed further active treatment due to rapid growth or clinically significant symptoms. Other authors have found similar percentage of patients that remain stable throughout the period observation, ranging from 42% to 79%.…”

Section: Discussionmentioning

confidence: 99%

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Head and neck paragangliomas: 30‐year experience

2020

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Background We aimed to review our experience and the changing trends in the management of head and neck paragangliomas (HNPG) over the last three decades. Methods We retrospectively reviewed 103 patients with HNPG treated at our center (1986‐2017). We included patients treated with surgery, radiotherapy, and patients maintained under active surveillance. Results Of the surgically treated patients (n = 79), 20% (12/59) of the carotid body tumors (CBT) had a cranial nerve deficit as sequela compared to 95% (19/20) of the non‐CBT. Radiotherapy controlled growth in all tumors treated with this modality (n = 10). Of the initially observed patients, 70% (14/20) remained stable and did not require additional treatment. Stratifying by decades, there was a progressive increase in patients initially attempted to be observed and a decrease in upfront surgery. No deaths attributable to the HNPG were encountered. Conclusions Surgery is an effective treatment for CBT. Nonsurgical treatment should be considered for non‐CBT.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Head and neck paragangliomas: 30‐year experience

2020

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“…Typically measuring around 3-5 mm, the carotid body's size can exceed 8 cm with repeated hypoxic stimulations (6) (4). As a chemoreceptor organ, it responds to acidosis, hypoxia, and hypercapnia, playing a vital role in autonomously regulating blood pressure, heart rate, respiration, and blood temperature by augmenting sympathetic ow (7).…”

Section: Discussionmentioning

confidence: 99%

Carotid Body Tumor (CBT): Incidental Discovery and Individualized Management

Senapati,

Kattamuri,

Deoker

2024

Preprint

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Carotid Body Tumors (CBT) are uncommon neuroendocrine neoplasms that develop near the carotid bifurcation. Most cases are asymptomatic and discovered incidentally. Diagnosis is based on imaging, with computed tomography being the preferred initial investigation. Surgical excision is the preferred treatment, with preoperative embolization and angiography aiding in the planning process. In cases where surgery is not feasible, radiotherapy may be considered. Here we present a 75-year-old female with recurrent vomiting, severe headache, and newly diagnosed atrial fibrillation. Workup incidentally detected carotid body paraganglioma. The patient's treatment included metoprolol for heart rate and blood pressure control and radiotherapy for CBT due to age and comorbidities. The discussion delves into the characteristics of paragangliomas, their chemoreceptor role, prevalence, and genetic factors. The case report emphasizes the importance of early detection and individualized approaches in managing CBTs, considering patient profiles and medical conditions.

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“…Bilateral tumors account for approximately 10% of the cases. Also, malignant tumors account for below 10% of CBTs [ 3 , 4 ].…”

Section: Introductionmentioning

confidence: 99%

Challenges in the Management of Massive Carotid Body Tumor

Olusoga-Peters,

Akinola,

Nwadiokwu

et al. 2024

Case Reports in Otolaryngology

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The carotid body paraganglioma is a rare benign neoplasm arising from the chemoreceptor cells of the carotid bulb. The carotid body has the largest collection of paraganglia in the head and neck with 60–70% of head and neck paraganglioma. Paraganglia are clusters of cells originating from the neural crest with histological and cytochemical characteristics of neuroendocrine cells. It is mostly asymptomatic in early presentation but become symptomatic and difficult to manage when the tumor is large. We present a case of a 26-year-old male who presented with a painless, pulsatile, progressively increasing left lateral neck swelling of 5 years duration with Shamblin IIIa. The diagnosis of the tumor was confirmed based on clinical features, histology, and radiological findings. We had difficult surgical dissection of the tumor with neurovascular damage.

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Carotid body tumors: A report of three cases and current literature review

Cited by 8 publications

References 10 publications

Head and neck paragangliomas: 30‐year experience

Head and neck paragangliomas: 30‐year experience

Carotid Body Tumor (CBT): Incidental Discovery and Individualized Management

Challenges in the Management of Massive Carotid Body Tumor

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