Carpenter's syndrome with empty sella and abnormal LRH and TRH response

Verdy, M; Dussault, Robert G.; Verrault, R.; Bolté, E

doi:10.1530/acta.0.1040006

Acta Endocrinologica

1983

DOI: 10.1530/acta.0.1040006

|View full text |Cite

Carpenter's syndrome with empty sella and abnormal LRH and TRH response

M Verdy¹,

Robert G. Dussault²,

R. Verrault³

et al.

Abstract: Two sisters with Carpenter's syndrome and empty sella have been evaluated for pituitary function. The TRH injection brought a normal response of TSH and prolactin. There were no change in FSH and LH, but a paradoxical increase of growth hormone and cortisol. The injection of LRH brought a normal response of FSH and LH, no change in TSH and cortisol values and a paradoxical increase in prolactin and growth hormone.

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

1988

2009

Publication Types

Select...

Article4

Relationship

Self Cite0

Independent4

Authors

Journals

Cited by 4 publications

(2 citation statements)

References 11 publications

(11 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Several studies reported that treatment with fenfluramine, also a serotonin increasing agent, leads to a reduction in blood lipids (2,22) and blood glucose (27,35). This effect could not always be explained by the decrease in body weight (2,35). To our howledge, the effect of fluoxetine on blood lipids has not been reported.…”

mentioning

confidence: 72%

“…Fluoxetine, a serotonin reuptake inhibitor, causes a reduction in body weight in obese patients (5,10,14,(18)(19)(20)24). Several studies reported that treatment with fenfluramine, also a serotonin increasing agent, leads to a reduction in blood lipids (2,22) and blood glucose (27,35). This effect could not always be explained by the decrease in body weight (2,35).…”

mentioning

confidence: 99%

See 1 more Smart Citation

No Specific Effect of Fluoxetine Treatment on Fasting Glucose, Insulin, Lipid Levels, and Blood Pressure in Healthy Men with Abdominal Obesity

Visser

Seidell²,

Koppeschaar

et al. 1994

Obesity Research

View full text Add to dashboard Cite

In this paper we investigated the effect of fluoxetine (60 mgd) on serum lipids, glucose and insulin concentrations and blood pressure by means of a randomized, double-blind placebo controlled trial. Thirty-eight overweight @MI: 26-30 kdm2), nondiabetic, nonhypertensive men with an abdominal fat distribution (waisffliip ratio: > 0.97) received dietary advice and placebo or fluoxetine for 12 weeks.The changes in serum parameters and blood pressure in the fluoxetine treated group were not different from the placebo treated group, despite a significantly larger weight loss in the fluoxetine group. In both groups serum total-cholesterol concentrations, serum LDL-cholesterol concentrations and tlie HDLLDL ratio were significantly improved after treatment. Reductions in fasting glucose concentration and systolic blood pressure were only significant in the placebo group. A reduction of serum triglycerides and an increase of HDL-cholesterol were found in the fluoxetine treated group.In the total study population the changes in serum lipids seemed to be more strongly related to the change in total body fat or subcutaneous abdominal fat (assessed by MRI) compared to the change in visceral fat. The improvement of most of the serum lipids was related to tlie change in total body fat independent of the mechanism for attaining this fat loss. Our results indicate that fluoxetine treatment has no specific effect beyond that expected for weight loss on serum lipid, glucose and insulin concentrations, and blood pressure in overweight men.

show abstract

mentioning

confidence: 72%

mentioning

confidence: 99%

No Specific Effect of Fluoxetine Treatment on Fasting Glucose, Insulin, Lipid Levels, and Blood Pressure in Healthy Men with Abdominal Obesity

Visser

Seidell²,

Koppeschaar

et al. 1994

Obesity Research

View full text Add to dashboard Cite

show abstract

Diabète insipide partiel et selle turcique vide au cours d'une histiocytose X

Caron

Bennet

Manelfe

et al. 1988

La Revue de Médecine Interne

View full text Add to dashboard Cite

Carpenter Syndrome

Hidestrand¹,

Vásconez

Cottrill

2009

Journal of Craniofacial Surgery

View full text Add to dashboard Cite

Carpenter syndrome is a rare autosomal recessive disorder that belongs to a group of rare craniosynostosis syndromes (Bull Soc Med Paris 1906;23:1310). Carpenter syndrome is the rarest, with only occasional patients seen. There are 3 common features in all of these syndromes: craniosynostosis (skull base abnormalities, with early fusion in different sutures), midface hypoplasia, and musculoskeletal abnormalities. Clinical features of Carpenter syndrome include peculiar facies, asymmetry of the skull, polydactyly, brachymesophalangy, mild soft tissue syndactyly, obesity, hypogenitalism, congenital heart disease, and mental retardation (J Pediatr 1966;69:1; Am J Roentgenol 1969;106). The brachycephaly is caused by early fusion in the coronal, sagittal, and lambdoidal sutures (Proc R Soc Med Sect Study Dis Child 1909). Most of the affected patients have a surgical procedure between 3 to 9 months of age to open the cranial vault to make space for the brain to grow (Plast Reconstr Surg 1978;62:335). We present a patient with Carpenter syndrome who is unusual in that she is an adult who has never had surgical intervention.

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

customersupport@researchsolutions.com

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Carpenter's syndrome with empty sella and abnormal LRH and TRH response

Cited by 4 publications

References 11 publications

No Specific Effect of Fluoxetine Treatment on Fasting Glucose, Insulin, Lipid Levels, and Blood Pressure in Healthy Men with Abdominal Obesity

No Specific Effect of Fluoxetine Treatment on Fasting Glucose, Insulin, Lipid Levels, and Blood Pressure in Healthy Men with Abdominal Obesity

Diabète insipide partiel et selle turcique vide au cours d'une histiocytose X

Carpenter Syndrome

Contact Info

Product

Resources

About