Carriage of Streptococcus Pneumoniae In Unvaccinated Toddlers At The Time of Pneumococcal Conjugate Vaccine Implementation Into The National Immunization Program In Poland
Abstract:We investigated pneumococcal carriage among unvaccinated children under five years of age at the time of conjugate polysaccharide vaccine (PCV) introduction into the national immunization program (NIP). Paired nasopharyngeal swab (NPS) and saliva samples collected between 2016 and 2020 from n=394 children were tested with conventional culture and using qPCR. The carriage rate detected by culture was 25.4% (97 of 394), by qPCR 39.1% (155 of 394), and 40.1% (158 of 394) overall. The risk of carriage was signific… Show more
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