2014
DOI: 10.4066/amj.2014.1926
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Carriage prevalence of carbapenem-resistant Enterobacteriaceae in stool samples: A surveillance study

Abstract: Screening for carriage of CRE in stools of patients undergoing elective or emergency gastrointestinal surgical procedures, with haematological malignancies taking chemotherapy, or those planned for bone marrow transplantation can guide clinicians about gut colonisation of multidrug-resistant Enterobacteriaceae as these groups of patients are at risk of possible endogenous infection.

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Cited by 25 publications
(16 citation statements)
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“…This is low compared to other countries in the Middle East such as Morocco (13%), India (9.9%) and Pakistan (18.3%). However, it is comparable to studies in Korea (0.3%) [12] , [19] , [31] , [32] . In addition, the prevalence of colonization of CRPAE is 6.5%, which is lower than studies performed in Spain (12%) and higher than those in France (3.4%) [8] , [13] , [33] .…”
Section: Discussionsupporting
confidence: 85%
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“…This is low compared to other countries in the Middle East such as Morocco (13%), India (9.9%) and Pakistan (18.3%). However, it is comparable to studies in Korea (0.3%) [12] , [19] , [31] , [32] . In addition, the prevalence of colonization of CRPAE is 6.5%, which is lower than studies performed in Spain (12%) and higher than those in France (3.4%) [8] , [13] , [33] .…”
Section: Discussionsupporting
confidence: 85%
“…The treatment of these organisms became more difficult because of their production of extended-spectrum β-lactamases (ESBLs), such as bla CTX-M , plasmid-mediated AmpC (pAmpC) or overexpression of chromosomal amp C gene [6] , [7] , [8] , [9] , [10] . Carbapenems became the last source for treatment of such organisms, which in turn has led to the emergence of carbapenem resistance under antibiotic selective pressure [8] , [11] , [12] . The global spread of carbapenem-resistant, Gram-negative rods is significantly increasing [1] , [2] , [13] .…”
Section: Introductionmentioning
confidence: 99%
“…Although six studies (40.0%) provided no formal definition for CAI versus HAI, four of these considered their entire sample ‘community’ because all isolates were obtained from outpatients [40,41,43,45]. Two separate definitions of CAI were used in the remaining nine studies.…”
Section: Resultsmentioning
confidence: 99%
“…Urine was the primary source of isolates [16,25,35,37,40,43], followed by faeces [29,41,45,46], intra-abdominal fluid [38,39,44], blood [42] and respiratory culture [36]. For the five studies only including CRE, K. pneumoniae was the most common organism [16,25,36,37], except a US-based study that had a slightly higher percentage of Enterobacter spp.…”
Section: Resultsmentioning
confidence: 99%
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