Carrier-free poly(glycyrrhetinic acid)-facilitated celastrol-loaded nanoparticle for high-efficiency low-toxicity treatment of rheumatoid arthritis

Zhang, Wenjing; Huang, Yuan; Li, Jing; Zhou, Mei; Huang, Weijun; Sun, Li; Gui, Shuangying; Li, Zhenbao

doi:10.1016/j.matdes.2024.112951

Materials & Design

2024

DOI: 10.1016/j.matdes.2024.112951

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Carrier-free poly(glycyrrhetinic acid)-facilitated celastrol-loaded nanoparticle for high-efficiency low-toxicity treatment of rheumatoid arthritis

Wenjing Zhang,

Yuan Huang,

Jing Li

et al.

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Cited by 2 publications

References 41 publications

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Navigating rheumatoid arthritis: insights into ligand-anchored nanoparticle strategies for anti-inflammatory therapy and relief

Karmarkar,

Fernandes,

Choonia

et al. 2025

RSC Pharm.

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Navigating rheumatoid arthritis: insights into ligand-anchored nanoparticle strategies for anti-inflammatory therapy and relief

Karmarkar,

Fernandes,

Choonia

et al. 2025

RSC Pharm.

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Supramolecular approach to the design of nanocarriers for antidiabetic drugs: targeted patient-friendly therapy

Vasileva,

Gaynanova,

Romanova

et al. 2024

RUSS CHEM REV

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Diabetes and complications derived are among serious global health concerns that critically deteriorate the quality of patient life and in some cases result in lethal outcome. Herein, general information on the pathogenesis, factors aggravating the course of the disease and drugs used for the treatment of two types of diabetes are briefly discussed. The aim of the review is to introduce supramolecular strategies that are currently being developed for the treatment of diabetes mellitus and are very effective alternative to chemical synthesis, which allows for fabrication of nanocontainers with switchable characteristics answering green chemistry criteria. Particular attention is paid to organic (amphiphilic and polymeric) formulations, including naturally driven compositions due to their biocompatibility, low toxicity, and bioavailability. Advantages and limitations of different nanosystems are discussed, with their adaptivity to noninvasive administration routes emphasized. <br> The bibliography includes 378 references.

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Carrier-free poly(glycyrrhetinic acid)-facilitated celastrol-loaded nanoparticle for high-efficiency low-toxicity treatment of rheumatoid arthritis

Cited by 2 publications

References 41 publications

Navigating rheumatoid arthritis: insights into ligand-anchored nanoparticle strategies for anti-inflammatory therapy and relief

Navigating rheumatoid arthritis: insights into ligand-anchored nanoparticle strategies for anti-inflammatory therapy and relief

Supramolecular approach to the design of nanocarriers for antidiabetic drugs: targeted patient-friendly therapy

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