Carriers of hemophilia A [letter]

Hemophilia: The Person, Family, and Nurse

“…Carriers of hemophilia usually have Factor VIII levels of approximately 30 to 70% (Kasper, 1976). Carriers of hemophilia A who have inherited the abnormal gene from their hemophiliac father have lower levels of Factor VIII coagulation activity than do those who have inherited the abnormal gene from their carrier mother (Rizza, et al, 1981). Laboratory testing is now available that can determine if a woman is a probable carrier.…”