Carvedilol/montmorillonite: Processing, characterization and release studies

Lakshmi, M. Suguna; Sriranjani, Muralidharan; Bakrudeen, Haja Bava; Kannan, Arumugam Suresh; Mandal, Asit Baran; Reddy, Boreddy S. R.

doi:10.1016/j.clay.2010.03.008

Cited by 24 publications

(11 citation statements)

References 26 publications

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“…The FTIR spectra, collected in Figure 3A and 3B, prove the presence of ionenes' chains in the montmorillonite gallery. MMT-Na is characterized by bands at 3620 cm [17,18]. FTIR spectra of ionenes show characteristic absorptions in the range of 3000-2860 cm -1 and 1490-1395 cm -1 corresponding to the stretching and deformation vibrations of C-H bonds, respectively.…”

Section: Resultsmentioning

confidence: 99%

Thermal stability and pollutant adsorption efficiency of nanocomposites consisted of clay and polymeric quaternary ammonium salts

Natkański

Kuśtrowski

Kochanowski

et al. 2011

Annales UMCS, Chemistry

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Polymer/layered silicate nanocomposites based on polymeric quaternary ammonium salts (ionenes) intercalated into the interlayer galleries of montmorillonite were synthesized. Zeta potential measurements were conducted to determine the amount of ionenes required to neutralize the negative charge of clay. The composition and structure of the obtained nanocomposites were examined by elemental analysis, ATR-FTIR and XRD. High dye sorption capacity was observed for the composite containing ionene 6,2.

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Section: Resultsmentioning

confidence: 99%

Thermal stability and pollutant adsorption efficiency of nanocomposites consisted of clay and polymeric quaternary ammonium salts

Natkański

Kuśtrowski

Kochanowski

et al. 2011

Annales UMCS, Chemistry

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“…In this regard, the usage of nanoparticle-based DDSs can be a very promising approach in two opposite directions: (i) To modulate drug dissolution (Class I) in order to achieve desired release kinetics and prolonged release and (ii) to improve the solubility of poorly water-soluble drugs (Class II) which represent the main group of APIs [15][16][17]. Synthetic-based polymer NPs may solve these problems for the oral delivering of proteins and vaccines.…”

Section: Nanoparticle Drug Delivery Systems Obtained From Synthetic Pmentioning

confidence: 99%

Synthetic Polymer-Based Nanoparticles: Intelligent Drug Delivery Systems

Andonova¹

2017

Acrylic Polymers in Healthcare

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One of the most promising strategies to improve the bioavailability of active pharmaceutical ingredients is based on the association of the drug with colloidal carriers, for example, polymeric nanoparticles, which are stable in biological environment, protective for encapsulated substances and able to modulate physicochemical characteristics, drug release and biological behaviour. The synthetic polymers possess unique properties due to their chemical structure. Some of them are characterized with mucoadhesiveness; another can facilitate the penetration through mucous layers; or to be stimuli responsive, providing controlled drug release at the target organ, tissues or cells; and all of them are biocompatible and versatile. These are suitable vehicles of nucleic acids, oligonucleotides, DNA, peptides and proteins. This chapter aims to look at the 'hot spots' in the design of synthetic polymer nanoparticles as an intelligent drug delivery system in terms of biopharmaceutical challenges and in relation to the route of their administration: the non-invasive-oral, transdermal, transmucosal (nasal, buccal/sublingual, vaginal, rectal and ocular) and inhalation routes-and the invasive parenteral route.

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“…Mt shows high thermal stability in the temperature region of 30-700°C with weight loss of 17% where 10% of weight loss from 30 to 150°C is attributed to the loss of adsorbed and interlayer water (Chen et al, 2010;Lakshmi et al, 2010). PLGA indicate single step mass loss from 247°C to 300°C assigned to the degradation of PLGA chains (Mathew et al, 2012;Seema and Datta, 2013).…”

Section: Tga Studiesmentioning

confidence: 99%