Cascade iatrogenesis: Factors leading to the development of adverse events in hospitalized older adults

Iatrogenic Factors in Psychopathology

“…In geriatrics, the concept of cascade iatrogenesis has been developed: the serial development of multiple medical complications that can be set in motion by a seemingly innocuous first event [58]. For instance, postoperative respiratory failure is common among elderly patients who underwent elective surgery or orthopedic treatment after a fracture; suffering an adverse event during hospitalization is strongly associated with a poorer prognosis following discharge [58].…”

“…For instance, postoperative respiratory failure is common among elderly patients who underwent elective surgery or orthopedic treatment after a fracture; suffering an adverse event during hospitalization is strongly associated with a poorer prognosis following discharge [58]. The concept is highly relevant to psychiatric practice.…”

Iatrogenesis–the biggest geriatric giant of all?–Hypocalcaemia with stridor and vocal cord paralysis in an older adult

“…Older adults are more susceptible to iatrogenic events [1,2] leading to increased morbidity and mortality. This case illustrated a series of iatrogenic events that affected the patient at different times in her life.…”

How can we keep patients with dementia safe in our acute hospitals? A review of challenges and solutions

“…In patients with dementia it is important to encourage mobility, even though this may increase the risk of falls. Patients with dementia are particularly prone to what is called 'cascade iatrogenesis', where a relatively innocuous first adverse event, which could have been prevented, leads to the serial development of multiple medical complications (15).…”