Cascade reaction and FRET-based fluorescent probe for the colorimetric and ratiometric signaling of hydrogen sulfide

Colorimetric and ratiometric fluorescent probe for hydrogen sulfide using a coumarin–pyronine FRET dyad with a large emission shift

“…The Förster resonance energy transfer (FRET) mechanism is widely used for designing the ratiometric uorescent probes because FRET-based probes can generally achieve a remarkable emission shi with two wellresolved emission bands, which will improve the accuracy by measuring the intensity ratio of these two emission bands. [26][27][28][29][30] Recently, several ratiometric uorescent H 2 S probes based on diverse FRET dyads have been developed (such as coumarin-rhodamine/uorescein, [31][32][33] coumarin-naphthalimide, 34 and coumarin-merocyanine); 35 however, most of these probes neither exhibit ordinary emission shis (<80 nm) nor a modest enhancement of the ratiometric signal (<100-fold) (Table S1 †). Although it is signicant to detect H 2 S in living biological samples, development of a FRET-based H 2 S probe with a large emission shi and a great ratiometric signal enhancement remains a challenge.…”

Recent progress in 0D optical nanoprobes for applications in the sensing of (bio)analytes with the prospect of global health monitoring and detailed mechanistic insights

“…Deoxyribonucleic acid (DNA) is a crucial nucleotide, which plays a key role in the course of life as it contributes to storing and transmitting genetic information. 277 Consequently, an infinitesimal alteration in the structure of DNA can affect in the genetic features of biological organisms, leading to serious disorders. 278 Therefore, for the quantitative detection of DNA, Gong et al designed methylene blue (MB)-modified poly(9,9-di- n -octyfluorenyl-2,7-diyl) (PFO)/poly[2-methoxy-5-(2-ethylhexyloxy)-1,4-(1-cyanovinylene phenylene)] (CN-PPV) Pdots, represented as Pdots@MB, using the nanoprecipitation method.…”

FRET‐based Fluorescent and Colorimetric Probe for Selective Detection of Hg(II) and Cu(II) with Dual‐mode

“…Zeng and co‐workers designed a FRET‐based fluorescent probe with the fluorescein analogue as the energy acceptor and the coumarin group as the energy donor. They found that this sensor with a detection limit of as low as 0.39 μM was highly selective and sensitive to H 2 S over other biologically relevant species . Han and co‐workers employed a phenothiazine donor and a rhodamine acceptor to construct a FRET‐directed ratiometric fluorescent probe with a low detection limit of 9.2 nM for selective response to Hg 2+ .…”