Cascaded contraction-expansion channels for bacteria separation from RBCs using viscoelastic microfluidics

Bilican, İsmail

doi:10.1016/j.chroma.2021.462366

Cited by 9 publications

(3 citation statements)

References 50 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…4E). 101 As single inlet devices are simple to operate, there are several other interesting sheathless cell sorting devices using viscoelastic focusing to achieve undiluted whole blood separation, 102 integration with positive magnetophoresis (Fig. 4F), 103 and a scaled-up double spiral design.…”

Section: Viscoelastic Focusingmentioning

confidence: 99%

Label-free microfluidic cell sorting and detection for rapid blood analysis

et al. 2023

View full text Add to dashboard Cite

show abstract

Section: Viscoelastic Focusingmentioning

confidence: 99%

Label-free microfluidic cell sorting and detection for rapid blood analysis

et al. 2023

View full text Add to dashboard Cite

show abstract

“…PDMS is a hydrophobic polymer with low surface tension. Thanks to this property, it has been used particularly in microfluidic systems, [44,45] and for altering surface tension in various applications. [46] The studies in the literature demonstrate that films obtained from natural polymers exhibit a hydrophilic structure.…”

Section: Contact Anglementioning

confidence: 99%

Preparation and Properties of Novel Mucilage Composite Films Reinforced with Polydimethylsiloxane

Bilican

2023

Macro Materials & Eng

Self Cite

View full text Add to dashboard Cite

Recently, there is an increasing interest in research on biodegradable, non‐toxic, and high‐strength biomaterials that can replace plastics, especially in the food industry. In this study, mucilage obtained from Linum usitatissimum seeds is used to develop a natural biodegradable biomaterial by reinforcing it with different concentrations of polydimethylsiloxane (PDMS). The biomaterials produced in the form of films are thoroughly investigated in terms of physicochemical (Fourier transform infrared spectroscopy, thermogravimetric analysis, scanning electron microscopy (SEM), energy dispersive X‐ray spectrum (EDX), atomic force microscopy (AFM), contact angle, and mechanical), biodegradable (in soil and water), and antibacterial properties. SEM‐EDX and AFM demonstrate the homogeneous distribution of PDMS throughout the mucilage matrix. The incorporation of PDMS improves the water solubility of the mucilage composite films, thereby enhancing their strength. It also imparts hydrophobic characteristics to the composite films. Thus, PDMS ensures the high barrier property of the composite films against water vapor. Furthermore, the addition of PDMS increases the antimicrobial properties of the mucilage composite films. The obtained results indicate that the first‐time produced mucilage‐PDMS composite films can serve as an alternative product for food packaging applications.

show abstract

“…In addition, size is a commonly employed label-free separation criterion in viscoelastic microfluidics . Researchers have demonstrated the use of viscoelastic fluids for the separation of two or more types of bioparticles having different sizes, including stem cells, cancer cells, − blood cells, , malaria parasite, fungi, bacteria, − extracellular vesicles (EVs), , and λ-DNA …”

Section: Introductionmentioning

confidence: 99%

Microfluidic Separation and Enrichment of Escherichia coli by Size Using Viscoelastic Flows

et al. 2023

View full text Add to dashboard Cite

Here, we achieve the separation and enrichment of Escherichia coli clusters from its singlets in a viscoelastic microfluidic device. E. coli, an important prokaryotic model organism and a widely used microbial factory, can aggregate in clusters, leading to biofilm development that can be detrimental to human health and industrial processes. The ability to obtain high-purity populations of E. coli clusters is of significance for biological, biomedical, and industrial applications. In this study, polystyrene particles of two different sizes, 1 and 4.8 μm, are used to mimic E. coli singlets and clusters, respectively. Experimental results show that particles migrate toward the channel center in a size-dependent manner, due to the combined effects of inertial and elastic forces; 4.8 and 1 μm particles are found to have lateral equilibrium positions closer to the channel centerline and sidewalls, respectively. The size-dependent separation performance of the microdevice is demonstrated to be affected by three main factors: channel length, the ratio of sheath to sample flow rate, and poly(ethylene oxide) (PEO) concentration. Further, the separation of E. coli singlets and clusters is achieved at the outlets, and the separation efficiency is evaluated in terms of purity and enrichment factor.

show abstract

Cascaded contraction-expansion channels for bacteria separation from RBCs using viscoelastic microfluidics

Cited by 9 publications

References 50 publications

Label-free microfluidic cell sorting and detection for rapid blood analysis

Label-free microfluidic cell sorting and detection for rapid blood analysis

Preparation and Properties of Novel Mucilage Composite Films Reinforced with Polydimethylsiloxane

Microfluidic Separation and Enrichment of Escherichia coli by Size Using Viscoelastic Flows

Contact Info

Product

Resources

About