Case 118: Proliferative Myositis

Demir, Mustafa Kemal; Beser, Mahmut; Akıncı, Okan

doi:10.1148/radiol.2442041504

Cited by 19 publications

(14 citation statements)

References 18 publications

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“…[2] The usual clinical presentation is of a painless, ill-defined, rapidly growing, firm, solitary lump in or adjacent to the muscles of the shoulder, thorax, thigh, or neck. [3] The lesion is usually 3 to 6 cm at presentation and is typically firm and deep-seated. Adults are usually affected with a peak incidence between 40 and 70 years of age.…”

Section: Discussionmentioning

confidence: 99%

“…The mass often evolves over the course of a few weeks and may double in size over several days. [3] Although their rapid growth and often bizarre microscopic appearance may suggest an aggressive course, these pseudosarcomas are clinically benign and rarely recur after subtotal excision. Consequently, the diagnosis always depends on histological evidence.…”

Section: Discussionmentioning

confidence: 99%

“…Lesions that arise from the subcutaneous tissue or from intermuscular fascia show the same characteristic histological features; hence, they are considered a fascial or subcutaneous variant of PM. [3] Several microscopic features are characteristic of PM. The alternation of proliferative connective tissue surrounding viable muscle fibers often gives rise to the so-called checkerboard effect which is characteristic of the disease.…”

Section: Discussionmentioning

confidence: 99%

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Rapidly growing chest wall mass mimicking a malignant tumor: proliferative myositis

Ergin¹

2011

Turkish J Thorac Cardiovasc Surg

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Rapidly growing chest wall mass mimicking a malignant tumor: proliferative myositis

Ergin¹

2011

Turkish J Thorac Cardiovasc Surg

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“…Although PM in this study appears as isointense comparing to the surrounding muscle on T1-weighted (T1w) image, 3,9,10,14,16,23,30 hypointense lesions have also been previously reported. 36,37 PM also appears as a hyperintense mass 9,10,12,14,16,28,29 with variable hypointense linear structures 12,16,25 on T2-weighted (T2w) image. These linear structures were correlated with preserved continuity of muscle bundle, also known as a "stripe sign."…”

Section: Imagingmentioning

confidence: 99%

Proliferative Myositis: A Comprehensive Review of 33 Case Reports

2019

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Proliferative myositis, a rare reactive intramuscular myofibroblastic proliferation, is not well recognized in clinical practice. It overgrows within a few weeks and expands the space between the muscle causing infiltrative-like border mimicking sarcoma. Knowledge of the natural history and pathology of proliferative myositis is essential in order to prevent misdiagnosis and unnecessary surgical resection. Thirty-three reported cases of proliferative myositis in PubMed and Web of Science databases from 2000 to 2018 had been reviewed with the main emphasis in clinical presentation, radiological and pathological findings, treatment, and prognosis. Both males (19 cases) and females (14 cases), predominantly the middle-aged and senior adults, were affected. Upper extremity and shoulder girdle were commonly involved. The chief complaint varied from either painful or painless mass. The traumatic injury was reported as a significant predisposing factor. The lesion typically proliferated and separated muscle bundle. Ultrasonography of the lesion revealed a characteristic “checkerboard pattern” on transverse view. The definite diagnosis was based on the demonstration of spindle-shaped fibroblast/myofibroblast admixed with giant ganglion-like cells in the biopsy. Immunohistochemistry may be useful diagnostic tool when the histopathology was inconclusive. Misdiagnosis of sarcoma occurred due to its rapid growth and infiltrative-like border. Watchful management without surgery was sufficient because of the potential for spontaneous regression. Thoroughly clinical examination and appropriate investigations, including imaging and histopathology, are crucial.

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“…Lesions are hyperintense on STIR sequences . MRI may occasionally show the persistence of muscle fiber orientation …”

mentioning

confidence: 99%