Case-control study of oral disease indexes in individuals with head and neck cancer after antineoplastic therapy

Abstract

Objective To evaluate the oral health of patients with head and neck cancer after antineoplastic treatment, and to compare them with patients with no history of cancer.Methods A total of 75 patients, divided into Study Group, composed of individuals after antineoplastic treatment (n=30), and Control Group, with individuals with no history of cancer (n=45), aged 37 to 79 years. The oral health status was evaluated through the index of decayed, missing or filled permanent teeth (DMFT), community periodontal index and evaluation of the use and need of prosthesis. All of these items were evaluated according to the criteria recommended by the World Health Organization. The statistical analysis was descriptive and used the Pearson’s χ2 test.Results The community periodontal index was higher in the Study Group when compared to the Control Group (p<0.0001). The need for an upper (p<0.001) and lower (p<0.0001) prostheses was higher in the Study Group. Also, the use of upper prosthesis was higher in the Study Group (p<0.002). The missing or filled permanent teeth index between the two groups (p>0.0506) and the use of lower prosthesis (p>0.214) did not present a relevant statistical difference.Conclusion Periodontal disease and edentulism are the most significant changes in individuals who received antineoplastic therapy for head and neck cancer as well as greater need for oral rehabilitation.

Assessment of oral health and care in head and neck oncology patients in King Faisal Specialist Hospital and Research Center-Jeddah

“…Some studies that recorded the DMFT score after cancer therapy reported higher scores than those in the present study ( Joyston-Bechal et al, 1992 , Tezal et al, 2013 , Quispe et al, 2018 , de Pauli Paglioni et al, 2019 ), while others have reported lower DMFT scores ( Dreizen et al, 1977 , Schwarz et al, 1999 , Michelet, 2012 , Dholam et al, 2013 , Venkataraghavan et al, 2014 , Gupta et al, 2016 ). One study recording DMFT scores after cancer therapy reported results comparable to those in the current study ( Bachok, Biswal et al, 2018 ).…”

Profile of cancer patients requiring dental and oral-maxillofacial prostheses in a Brazilian subpopulation

“…Quispe et al . ( 17 ) evaluated 75 individuals, but only 30 were cancer patients. The authors assessed the need for maxillary and mandibular prostheses and found the following results: 21 patients needed a maxillary prosthesis to replace one tooth (10%) or to replace more than one tooth (33.3%), needed a combination of prostheses (13.3%) or needed a total prosthesis (13.7%) and 29 patients used a mandibular prosthesis to replace more than one tooth (70%), required a combination of prostheses (3.3%) or required a total prosthesis (23.7%).…”

Implicações da radioterapia no tratamento do Glioma de baixo grau na odontologia: relato de caso

“…No período durante a radioterapia os pacientes apresentaram queda no estado geral, porém com o término do tratamento foi verificado melhora considerável no estado geral dos pacientes. No estudo transversal de Quispe et al 27 não houve diferença estatística significativa na prevalência de cárie dentária entre o grupo estudo e o grupo controle, porém a doença periodontal foi mais prevalente no grupo estudo, com 90,7%, diante de 60% do grupo controle. Os tecidos periodontais podem sofrer mudanças após o tratamento, podendo acontecer recessão gengival, perda de inserção gengival e elevado índice de placa bacteriana.…”

“…Em 2018, com o objetivo de avaliar a saúde bucal de pacientes com câncer de cabeça e pescoço após tratamento antineoplásico, e compará-los com pacientes sem histórico de câncer, Quispe et al 27 , realizaram um estudo transversal com indivíduos de ambos sexos, maiores de 18 anos de idade, divididos em Grupo de Estudo (GE) e Grupo Controle (GC). O GE foi composto por pacientes com câncer de cabeça e pescoço após concluir o tratamento que incluiu cirurgia, radioterapia e/ou quimioterapia.…”