Case for diagnosis

Cherobin, Ana Carolina Figueiredo Pereira; Oliveira, Felipe Osta de; Baeta, Isabela Guimarães Ribeiro; Vale, Everton Carlos Siviero do

doi:10.1590/s0365-05962012000100025

Cited by 4 publications

(7 citation statements)

References 8 publications

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“…The most difficult differential diagnosis is with ashy dermatosis, this, however, affects brown skinned patients, with a tropism for the torso and limbs (and not for intertriginous areas) and with erythematous borders on the edges of active lesions. 1,3,5-8 Microscopically, one can observe a lichen planus in regression. There is epidermic atrophy with irregular hydropic degeneration on the basal layer and an absence of epidermic hyperplasia (usually present on lichen planus).…”

Section: Discussionmentioning

confidence: 99%

Lichen planus pigmentosus inversus

Barros¹,

Almeida

Dinato

et al. 2013

An. Bras. Dermatol.

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Twenty-five year old male patient presenting with asymptomatic brown spots, on cervical, axillary, inguinal and popliteal regions, for the last nine months. Pathological examination showed hydropic degeneration of the basal layer, pigmentary incontinence and moderate inflammatory lymphocytic infiltrate in the dermis. Lichen planus pigmentosus inversus is a rare subtype of lichen planus characterized by hyperchromic, asymptomatic or mildly pruritic macules, measuring from millimeters to centimeters in diameter, with defined borders, affecting intertriginous areas, most commonly in the axillae and groin of Caucasian patients. It presents unique lichenoid histology. We report a case with typical clinical features, histology and evolution.

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Section: Discussionmentioning

confidence: 99%

Lichen planus pigmentosus inversus

Barros¹,

Almeida

Dinato

et al. 2013

An. Bras. Dermatol.

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“…Such morphological findings, though subtle, suggest the clinical hypothesis ashy dermatosis (Persistent Dyschromatic Erythema) as well as postinflammation pigmentation. 4 Lightening lotion (Arbutin 4%, Chromabright 0.5%, Alf abisabol 1%, Nicotinamide 4%, Kojico Acid 3%, Nonionic Cream) was then prescribed por use at night on all spots, and after 30 days, it was observed that lightening of the macules and skin rejuvenation occurred. However, there was no lightening of the inframammary region and of the upper limbs' macules.…”

Section: Case Reportmentioning

confidence: 99%

“…This border is present in acute lesions, but may be replaced by a hypochromic halo. [4][5][6][7][8][9][10][11][12] An important fact is that ashy dermatosis appears more often in patients with darker colored skin, but the patient reported is white.…”

Section: Ashy Dermatosismentioning

confidence: 99%

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Ashy Dermatosis - A Case Report From Palmas - To

Borges¹,

Azzam²,

Gomes³

et al. 2019

Rev Pat Tocantins

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INTRODUCTION: Ashy dermatosis is a rare dermatosis of unknown etiology and pathogenesis, more common in people with darker skin. However, in this case report, the patient is white. CASE REPORT: A 54-year-old white woman with a history of asymptomatic gray-stained macules located on the craniocaudal axis. Despite a positive antinuclear antibody (ANA) test, the use of Plaquinol was suspended due to the fact that the patient did not present rheumatologic affections. A biopsy compatible with the condition of ashy dermatosis and post-inflammation pigmentation was performed. However, the anatomopathological examination revealed superficial perivascular dermatitis with pigmented incontinence and skin fragments, a discreet superficial perivascular inflammatory mononuclear infiltrate and mild pigmentary incontinence, confirming the clinical hypothesis of ashy dermatosis. A skin lightening lotion (Arbutin 4%, Chromabright 0.5%, Alfabisabol 1%, Nicotinamide 4%, Kojico Acid 3%, Nonionic Cream) was used for 30 days with satisfactory results, along with the substitution of antihypertensive medication. FINAL CONSIDERATIONS: The report is relevant because it is necessary to know this pathology for differential diagnosis of pigmented dermatosis and so that the best treatment can be prescribed. Keywords: Ashy Dermatosis; Hyperpigmentation; Erythema Dyschromicum Perstans. RESUMO INTRODUÇÃO: A dermatose cinzenta é uma dermatose rara, de etiologia e patogenia desconhecida, mais comum em pessoas de pele mais escura, porém no caso relatado a paciente é branca. RELATO DE CASO: Mulher de 54 anos de idade, branca, com história de máculas de coloração acinzentada, assintomáticas, localizadas no eixo craniocaudal. Apesar do FAN positivo, o uso de Plaquinol foi suspenso pela paciente não apresentar afecção reumatológica. Foi realizada uma biópsia compatível com o quadro de dermatose cinzenta bem como pigmentação pós-inflamação. No entanto, no exame anatomopatológico foi encontrada dermatite perivascular superficial com incontinência pigmentar e em fragmentos de pele, um discreto infiltrado inflamatório mononuclear perivascular superficial e leve incontinência pigmentar, confirmando a hipótese clínica de dermatose cinzenta. Uma loção clareadora (Arbutin 4%, Chromabright 0,5%, Alfabisabol 1%, Nicotinamida 4%, Ácido Kojico 3%, Creme não iônico) foi utilizada por 30 dias apresentando resultados satisfatórios, além da substituição do anti-hipertensivo. CONSIDERAÇÕES FINAIS: O relato é relevante pois deve-se conhecer essa patologia para diagnose diferencial das dermatoses pigmentadas e desta forma optar pela melhor conduta terapêutica. Palavras-chave: Dermatose cinzenta; Hiperpigmentação; Eritema Discrômico Persistente.

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“…EDP, also known as ashy dermatosis, is a rare acquired idiopathic hypermelanosis. The etiology remains unknown, however several predisposing factors have been proposed, such as drugs (antibiotics, benzodiazepines, pesticides), endocrinopathies or infectious disorders such as human immunodeficiency virus infection and hepatitis C. 4 - 6 The main differential diagnosis of EDP is pigmented lichen planus (usually shiny purple, flat-topped, firm papules often crossed by fine white lines) however, lichen planus often involves mucous membranes and is associated with mild pruritus, neither characteristics were present in this boy. Idiopathic eruptive macular pigmentation would be another differential hypothesis, however this condition shows typically with brownish and non confluent lesions.…”

mentioning

confidence: 99%

Erythema dyschromicum perstans in a child following an enteroviral meningitis

Melo¹,

Sá

Carvalho³

2017

An. Bras. Dermatol.

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A healthy 6-year-old boy presented with an erythematous macular exanthema, meningeal signs and fever, initially diagnosed with probable bacterial meningitis and treated with antibiotic and anti-inflammatory drugs. Enteroviral meningitis was confirmed, but the skin lesions continued to evolve and the patient was ultimately diagnosed with erythema dyschromicum perstans. The boy was followed during three years until the spontaneous resolution of the dermatosis.

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Case for diagnosis

Cited by 4 publications

References 8 publications

Lichen planus pigmentosus inversus

Lichen planus pigmentosus inversus

Ashy Dermatosis - A Case Report From Palmas - To

Erythema dyschromicum perstans in a child following an enteroviral meningitis

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Case for diagnosis

Cited by 4 publications

References 8 publications

Lichen planus pigmentosus inversus

Lichen planus pigmentosus inversus

Ashy Dermatosis - A Case Report From Palmas - To

Erythema dyschromicum perstans in a child following an enteroviral meningitis

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Ashy Dermatosis - A Case Report From Palmas - To