Case-matched comparison of ABO-incompatible and ABO-compatible living donor liver transplantation

Abstract

The short-term outcomes of ABO-I LDLT were comparable to those of ABO-C LDLT in this study. ABO-I LDLT is an effective and safe transplant option with the potential to expand the pool of live donors.

Race/ethnicity is associated with ABO‐nonidentical liver transplantation in the United States

“…In the LT literature, a 2012 retrospective study of the UNOS database of A2 → O ABO‐nonidentical LT showed that A2 → O mismatches to be safe with similar patient and graft survival to O → O ABO‐identical LT . The acceptability of A2 → O ABO‐incompatible transplantation has also been independently demonstrated in Europe and Asia . When we analyzed the distribution of A2 → O transplantation, we found significant regional variation with most of these operations taking place in regions 5 (23%), 2 (14%), 11 (13%), and 3 (10%).…”

“…LT. 22 The acceptability of A2 → O ABO-incompatible transplantation has also been independently demonstrated in Europe and Asia. [23][24][25] When we analyzed the distribution of A2 → O transplantation, we found significant regional variation with most of these operations taking place in regions 5 (23%), 2 (14%), 11 (13%), and 3 (10%). These This study has several limitations.…”

Pancreas transplantation using compatible but non‐identical ABO blood group donors

“…There are variable data on outcomes for liver, kidney, heart, lung, and intestine transplantation using NIC donors . There are, however, no data regarding pancreas transplantation using NIC donors.…”

“…There are variable data on outcomes for liver, kidney, heart, lung, and intestine transplantation using NIC donors. [6][7][8][9][10][11][12][13][14] 19 Patients listed for SPK also have been shown to have higher life years from transplant (LYFT) than kidney recipients. 20 Thus, utilization of pancreas and kidney transplantation for this patient population can be considered as an optimal utilization of a limited resource.…”

“…There are emerging studies regarding intestine transplantation that may suggest that NIC intestine/multi‐visceral transplants may have higher rates of rejection . Kim et al reported comparable outcomes for ABO NIC and identical liver transplants. Numerous reports have been published documenting hemolysis in NIC liver, kidney and intestine transplants .…”