Case of atypical lipomatous tumor: Possible usefulness of ultrasonography for diagnosis

Itani, Yoshihito; Oiso, Naoki; Yanagihara, Shigeto; Okahashi, Kazunori; Isogai, Noritaka; Kawada, Akira

doi:10.1111/1346-8138.14911

Cited by 1 publication

(1 citation statement)

References 4 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The diagnosis of ALT was based on histological assessment according to the WHO criteria (20)(21)(22), and all surgical specimens were reviewed and diagnosed by two pathologists who were experienced in the diagnosis of softtissue tumors, as previously described (23). In brief, the subjects of the study were histologically characterized by the presence of atypical spindle or pleomorphic stromal cells within often thickened fibrous septa, associated with or without mono-or multivacuolated lipoblasts (23,24). ALT is classified into two subtypes-superficial type, such as a fat-layer origin, and deep type, such as a muscle-layer or a retroperitoneum origin-in accordance with the occurrence sites, as previously described (3).…”

Section: Patientsmentioning

confidence: 99%

A Retrospective Study of Superficial Type Atypical Lipomatous Tumor

et al. 2020

View full text Add to dashboard Cite

Atypical lipomatous tumor (ALT) has been defined as a well-differentiated liposarcoma exhibiting a higher frequency of a local recurrence after surgical resection. ALT is mainly classified into deep type and superficial type. Compared with deep type ALT, superficial type ALT is rarely observed. One of the most important issues is that little has been known about superficial type ALT and it is not easy to predict the presence of superficial type ALT before surgical resection. To clarify the clinical manifestations of superficial type ALT, we examined 15 cases with superficial type ALT and 118 cases with benign lipoma, and analyzed their differences in clinical characteristics and the findings of MRI test. In clinical characteristics, the tumor size of superficial type ALT was significantly greater than that of benign lipoma, and superficial type ALT showed a significantly higher frequency of the tumor size of more than 4 cm. Superficial type ALT exhibited poor tumor mobility and hardness with elastic soft. In addition, a significantly higher frequency of tumor location of superficial type ALT was observed in extremities. Among tumor sites at the trunk, buttocks, and shoulder were high frequent location in superficial type ALT. In an MRI examination, superficial type ALT exhibited a significantly higher frequency of the septal structures compared with benign lipoma. The combinations of clinical characteristics, including physical examinations, MRI, and histological examinations, are helpful for the diagnosis of superficial type ALT.

show abstract