Case of Hypopituitary Coma with Serial Electroencephalography

Salmon, Hannah

doi:10.1136/bmj.1.4980.1397

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Cited by 8 publications

(2 citation statements)

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“…The clinical aspects of untreated cortisone deficiency with regard to mental disturbance include depression, impaired mentation, and mild neurotic traits to gross psychosis 8 . There have been case reports of recoverable cognitive impairment after treatment of hypopituitary coma 9 – 12 . In these cases, the roles of hypoglycemia, hypotension, and adrenal insufficiency were considered important factors in the development of cognitive impairment.…”

Section: Discussionmentioning

confidence: 99%

Cortisol Deficient State

Basavaraju¹,

Phillips²

1989

J American Geriatrics Society

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An elderly female who had suffered a stroke was admitted to the Jewish Institute for Geriatric Care (JIGC) for rehabilitation. Three years previously she was found to have a pituitary macroadenoma (prolactinoma) that was treated with radiation therapy. She had been on thyroid replacement for secondary hypothyroidism. Upon admission she was found to have severe cognitive impairment in association with a low plasma cortisol level. After treatment with prednisone there was a dramatic improvement in cognitive function and the patient was able to participate in a rehabilitation program.

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Section: Discussionmentioning

confidence: 99%

Cortisol Deficient State

Basavaraju¹,

Phillips²

1989

J American Geriatrics Society

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“…delta activity." Serial E.E.G.s have been taken in a case of hypopituitary coma by Salmon (1956). The coma was associated with hypothermia (870 F.; 30.6°C.…”

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confidence: 99%