Case of severe acute lupus myocarditis and multiple-organ failure

Abstract

We report a case of severe lupus myocarditis with rapid, acute deterioration to cardiogenic shock and multiorgan failure, highlighting the importance of early identification and treatment of acute presentations in patients with systemic lupus erythematosus. A 31-year-old woman with previously diagnosed subacute cutaneous lupus erythematosus initially presented with abdominal pain and frank per-rectal bleeding. She deteriorated rapidly with type 1 respiratory failure and acute kidney injury requiring dialysis secondary to acute cardiac failure with a prolonged intensive care unit admission, over a month. A significantly elevated troponin, global hypokinesia on echocardiogram and normal coronary artery angiogram and cardiac MRI lead to the diagnosis of acute lupus myocarditis as the cause for the cardiogenic shock. She was treated with high-dose corticosteroids and eventually made a full recovery, with cardiac function returning to normal.

Effect of replacement therapy (CRRT) and hemodialysis (IHD) on severe acute renal failure

“…Significant advancements in the diagnosis and treatment of ARF have been made recently. However, the spectrum of its primary disease has also undergone major changes, from simple ARF to acute, complex and more severe SARF (severe acute renal failure) (Hawkins et al, 2018).…”