Case of solitary plasmacytoma of tibia

Madi, Sandesh; Pandey, Vivek; Sharma, Akhya; Monappa, Vidya

doi:10.1136/bcr-2018-227546

Cited by 1 publication

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“…Changes in renal function and the blood calcium level, multiple bone damage sites, abnormal immune protein indexes, and an abnormal Kappa-light chain/Lambda-light chain ratio are features that help diagnose MM. [ 8 ] In our case, the patient had a bone marrow lesion in the middle and upper segment of the right tibial trunk, <2% of plasma cells, and normal renal function and serum calcium distribution.…”

Section: Discussionmentioning

confidence: 72%

Solitary bone plasmacytoma of the tibia presenting as chronic osteomyelitis: A rare case report and literature review

et al. 2023

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Rationale: Plasmacytoma is a rare plasma cell dyscrasia that grows within the axial skeleton or soft tissue structures as solitary or multiple masses. The primary types are solitary plasmacytoma, including solitary bone plasmacytoma (SBP) and solitary extramedullary plasmacytoma, and multiple solitary plasmacytomas. SBP is characterized by localized proliferation of monoclonal plasma cells and is rare. However, SBP with chronic osteomyelitis is even rarer. Patient concerns: A 47-year-old man previously diagnosed with chronic osteomyelitis presented with repeated discharge and ulceration in the front of his right tibia. Diagnosis, interventions and outcomes: Lower extremity magnetic resonance imaging (MRI) and computed tomography (CT) examinations showed dead bone formation and surrounding inflammatory edema. Thus, the patient underwent dead bone excision and fenestration of the bone marrow cavity. The histopathologic examination results indicated plasmacytoma. Therefore, we administered radiotherapy with satisfactory results. Lessons: Physicians should pay close attention to chronic osteomyelitis because it may be accompanied by plasmacytoma. Postoperative pathological and immunohistochemical examinations are crucial, and surgical resection of the lesion and local radiotherapy are effective treatment methods.

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Section: Discussionmentioning

confidence: 72%