Case report: A case of primary renal carcinoid tumor

Chen, Chung-Tso; Hsieh, Shu-Wei; Hsieh, Tung‐Han

doi:10.1016/j.eucr.2018.07.020

Cited by 7 publications

(9 citation statements)

References 5 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…However, some literature showed that the primary renal carcinoid was a hypoxic tumor with no enhancement or mild enhancement. [ 2 , 10 ] 1 of our cases presented mild enhancement with slight delayed enhancement in the parenchymal and excretory phases.…”

Section: Discussionmentioning

confidence: 60%

“…And CT findings usually demonstrate a realistic/cystic solid mass with calcification and mild contrast enhancement of solid components, which could be used for diagnosis and differential diagnosis. [ 2 ] All our 3 cases of primary RCT were found with calcification in the lesion. On CT, they were heterogeneously enhanced but less than the renal cortex in corticomedullary phase.…”

Section: Discussionmentioning

confidence: 92%

“…[ 3 ] In addition, some of the symptoms of RCT include abdominal or lumbago, hematuria, constipation, frequent urination, fever and a loss of weight. [ 2 , 4 ] The vasoactive substances (serotonin) produced by tumors cause clinical manifestations of carcinoid syndrome such as blushing or diarrhea. [ 5 , 6 ] About 13% RCT patients show carcinoid syndrome, [ 5 ] but none of our cases showed this clinical manifestation.…”

Section: Discussionmentioning

confidence: 99%

“…There are just almost 100 cases of carcinoid tumors in kidney since the first case was reported in 1966. [ 2 – 4 ] Most of the primary renal carcinoid tumors (RCT)are misdiagnosed due to lack of the specific clinical manifestations. Therefore, radiological evaluation of primary RCT can be challenging.…”

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Primary renal carcinoid tumors

Chen

Shu

et al. 2021

Medicine

View full text Add to dashboard Cite

Rationale: Primary renal carcinoid tumors are very rare and only about 100 cases have been reported in the medical literature. There are even fewer articles on the imaging manifestations of primary renal carcinoid tumors. Patient concerns: We present 3 cases of patients with lumbago and hematuria. These were cases of primary renal carcinoid tumors with initial suspicion of suprarenal epithelioma. Diagnoses: Renal lesions were detected on abdomen computed tomography (CT) imaging. The 3 cases presented as solid/cystic solid renal mass with uniform or non-uniform density, calcification in the mass, and enhanced heterogeneity. Interventions: The laparoscopic partial/radical nephrectomy were performed. Outcomes: The postoperative histological diagnosis were primary renal carcinoid tumors. Case 2 been lost to follow-up in 3 patients, and the other 2 patients (Case 1 and 3) are still alive. Case 1 had intrahepatic metastases. Lessons: Primary renal carcinoid tumors mostly present as solid mass/cystic solid mass with calcification and delayed enhancement of heterogeneity on CT imaging, but the diagnosis depends on pathological diagnosis. Hence, raising awareness of the CT features of the rare tumor in the kidney may broaden the knowledge base of radiologists.

show abstract

Section: Discussionmentioning

confidence: 60%

Section: Discussionmentioning

confidence: 92%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Primary renal carcinoid tumors

Chen

Shu

et al. 2021

Medicine

View full text Add to dashboard Cite

show abstract

“…Neuroendocrine tumors (NET) can occur anywhere in the human body, but in more than 90% of cases, they are found in the gastrointestinal tract or the respiratory tract [1]. NETs in the genitourinary system are only found in very small numbers, and primary renal NET is extremely rare [2].…”

Section: Introductionmentioning

confidence: 99%

Primary renal well-differentiated neuroendocrine tumors: report of six cases with an emphasis on the Ki-67 index and mitosis

Kim

Moon

2019

Diagn Pathol

View full text Add to dashboard Cite

BackgroundPrimary renal well-differentiated neuroendocrine tumors (WDNETs) also called carcinoid and atypical carcinoid are extremely rare, and little is known about parameters that may predict prognosis at diagnosis.MethodsSix cases of primary renal WDNET were collected. After reviewing slides stained with hematoxylin and eosin, proportions of each growth pattern were determined. Synaptophysin, chromogranin, CD56, and Ki-67 immunostaining and Ki-67 morphometric analysis were performed.ResultsPatients included three female and three males, mean age was 53.3 years. The mean tumor size was 4.5 cm, three cases were greater than 5 cm. At the time of initial surgery, lymph node and/or distant metastasis was confirmed in two cases. In a third case, no metastasis was initially found, but lymph node metastasis was identified during follow-up. The remaining three cases did not exhibit metastasis. Histopathologically, the renal WDNETs were primarily composed of ribbon-like and sheet-like growth patterns. Most of the tumors were diffusely positive for neuroendocrine markers. Mitotic count was high (≥2/10HPF) in cases with lymph node or distant metastasis but was low (< 2/10HPF) in non-metastatic cases. Furthermore, the Ki-67 index was also higher (≥3%) in the cases with metastases than in cases without metastasis.ConclusionThree out of the six primary renal WDNETs demonstrated aggressive behavior and exhibited increased mitotic counts and Ki-67 indices. These results suggest that mitosis and the Ki-67 index could be used as prognostic indicators for renal WDNET.

show abstract