2023
DOI: 10.4269/ajtmh.22-0313
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Case Report: A Case of Post-Transplant Chagas Reactivation after Negative Trypanosoma cruzi Testing

Abstract: Patients with Chagas cardiomyopathy carry a significant risk of reactivation after heart transplantation. Reactivation of Chagas disease can lead to graft failure or systemic complications such as fulminant central nervous system disease and sepsis. As such, careful screening for Chagas seropositivity prior to transplant is crucial to preventing negative outcomes in the post-transplant setting. One challenge in screening these patients is the variety of laboratory tests available and their differing sensitivit… Show more

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