“…G6PD deficiency reportedly affects 2.2–14% of the north Indian population, and co-existence of both illnesses, though rare, has been documented 2,3. Acute viral hepatitis and HEV per se can lead to mild hemolysis; however, cases of severe hemolysis with markedly raised bilirubin with acute kidney injury, as in our patient, are very rare 3,4. Our patient had severe intravascular hemolysis, as evidenced by the rapid fall in hemoglobin, marked elevation in mixed hyperbilirubinemia, hemoglobinuria, and markedly raised plasma LDH.…”