Case report: COVID-19 infection in a pregnant 33-year-old kidney transplant recipient

Abstract

Patients facing severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) infections with comorbidities, especially patients whose immune system is weakened have higher chances to face severe outcomes. One of the main reasons behind the suppression of the immune system is iatrogenic, in patients who have autoimmune diseases and/or had an organ transplant. Although there are studies that are examining immunocompromised and/or transplanted patients with COVID-19 infection, furthermore there is a limited number of studies available which are dealing with COVID-19 in pregnant women; however, it is unique and is worth reporting when these factors are coexisting. In this study, we present the case of a 33-year-old Caucasian pregnant woman, who had a kidney transplant in 2009 and contracted the SARS-CoV-2 virus on the 26th gestational week, in 2021. After her infection, superimposed preeclampsia was diagnosed and due to the worsening flowmetric parameters, she gave birth to a premature male newborn with cesarean section. Our kidney transplant patient’s case highlights how COVID-19 disease can lead to preeclampsia and artificial termination of gestation.

A meta-analysis on first-trimester blood count parameters—is the neutrophil-to-lymphocyte ratio a potentially novel method for first-trimester preeclampsia screening?

“…NLR was studied in pregnant COVID-19 patients as well ( 74 , 75 ): Aydin Güzey et al ( 76 ) evaluated 254 cesarean sections with COVID-19 and found elevated levels of NLR among the symptomatic patients. Our research group also presented a case report where we found elevated NLR in a preeclamptic COVID-19 patient ( 77 ). Our research group additionally conducted a case–control study, which included 45 pregnant patients with COVID-19.…”

Predicting Potentially Fatal COVID-19 Disease in Pregnant Patients Using the Neutrophil-to-Lymphocyte Ratio (NLR)

“…Our research group previously reported the case of a 33-year-old pregnant kidney transplant recipient patient. During her COVID-19 illness, her NLR values were elevated, she required non-invasive respiratory support, and she exhibited pre-eclamptic symptoms [34]. After reporting this interesting case, our focus shifted to researching NLRs in pregnant COVID-19 patients.…”