Case Report: Dental Treatment of a Child with Hypophosphataemic Rickets

Coelho, Ana Sofia Estima da Cunha; Marques, Priscila Garcia; Canta, João Pedro

doi:10.1007/bf03262608

Cited by 3 publications

(4 citation statements)

References 7 publications

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“…Phosphate is the main component of hydroxyapatite (Ca 10 (PO 4 ) 6 (OH) 2 ) and essential in cell metabolism (adenosine triphosphate (ATP)) [ 11 ]. Homeostasis of serum phosphate levels are controlled by renal absorption, bone resorption, and hormonal (calcitriol, parathyroid hormone (PTH), and fibroblast growth factor 23 (FGF23)) regulation of intestinal absorption [ 5 , 11 ]. Subsequent hypophosphatemia, thus, impairs mineralisation of the teeth, bones, and cartilage [ 5 , 13 ].…”

Section: Introductionmentioning

confidence: 99%

“…Clinical features include bowing of lower extremities, disproportionately short stature, cranial osseous deformities, and dental manifestations [ 5 , 12 , 14 ]. The dental presentation is significant and associated with a lifelong burden of restorative and oral surgical intervention.…”

Section: Introductionmentioning

confidence: 99%

“…The dental presentation is significant and associated with a lifelong burden of restorative and oral surgical intervention. The most common clinical presentation is multiple recurrent dental abscesses in noncarious teeth, and in some patients, this may be the first clinical manifestation of their disease [ 4 , 5 ]. Defects in dentine mineralisation, thin, hypoplastic enamel, enlarged pulp chambers extending to the enamel–dentine junction (EDJ), and root resorption are commonly cited [ 4 – 6 , 11 , 14 , 15 ].…”

Section: Introductionmentioning

confidence: 99%

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Hypophosphataemic Rickets Secondary to Raine Syndrome: A Review of the Literature and Case Reports of Three Paediatric Patients’ Dental Management

Hirst

Abou-Ameira

Critchlow

2021

Case Reports in Pediatrics

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Raine Syndrome (RS) also referred to as lethal osteosclerotic bone dysplasia describes an exceptionally rare autosomal recessive disorder with an estimated prevalence of <1 in 1,000,000. Endocrinological manifestations such as hypophosphataemic rickets depict a recent finding within the phenotypic spectrum of nonlethal RS. The dental sequelae of hypophosphataemic rickets are significant. Spontaneous recurrent abscesses on noncarious teeth result in significant odontogenic pain and multiple dental interventions. The dental presentations of nonlethal RS are less widely described within the literature. Amelogenesis Imperfecta (AI), however, was recently postulated as a key characteristic. This article presents the dental manifestations and extensive restorative and oral surgical intervention of three siblings with hypophosphataemic rickets secondary to Raine Syndrome treated at Great Ormond Street Hospital for Children, a tertiary referral hospital.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Hypophosphataemic Rickets Secondary to Raine Syndrome: A Review of the Literature and Case Reports of Three Paediatric Patients’ Dental Management

Hirst

Abou-Ameira

Critchlow

2021

Case Reports in Pediatrics

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“…Other causes of rickets include renal diseases, medications and malabsorption syndrome. [ 13 ] Rickets develop when the growing bones fail to mineralise. Various types of rickets are nutritional rickets, vitamin D-dependent rickets, hypophosphatemic vitamin D-resistant rickets, and X-linked hypophosphataemia.…”

Section: Discussionmentioning

confidence: 99%

Rickets – A case report

Mudgade,

Srivastava,

Qureshi

et al. 2023

Journal of Oral and Maxillofacial Pathology

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Rickets is a disorder caused by a lack of vitamin D, calcium or phosphate. It leads to softening and weakening of the bones. Dental manifestation of rickets includes enamel hypoplasia and delayed tooth eruption. The most important oral findings are characterised by spontaneous gingival and dental abscesses occurring without a history of trauma or caries. Radiographic examination revealed large pulp chambers, short roots, poorly defined lamina dura and hypoplastic alveolar ridge. These dental abscesses are common, and therefore, extraction and pulpectomy are the treatment of choice. Oral manifestations of rickets should be diagnosed early by both physicians and dentists to prevent severe dental complications. This article aims to report a case of rickets in a 3-year-old girl, describing the dental findings and the treatment to be performed in these cases.

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