Case Report: Fusion of positron emission tomography (PET) and computed tomography (CT) images for image-guided endoscopic navigation in maxillofacial surgery: Clinical application of a new technique

Feichtinger, Matthias; Aigner, Reingard; Santler, Gert; Kärcher, Hans

doi:10.1016/j.jcms.2007.05.004

Cited by 11 publications

(7 citation statements)

References 32 publications

(27 reference statements)

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“…As PET/CT image-guided navigation shows high precision when navigating surgical tools near delicate structures, especially in the midface or skull base region (Feichtinger et al, 2007;Feichtinger et al, 2008), it may also have potential for improving the outcomes of resected oral cavity and oropharynx T4b tumours and maxillary sinus and nasal cavity T4a tumours.…”

Section: Discussionmentioning

confidence: 99%

Intraoperative control of resection margins in advanced head and neck cancer using a 3D-navigation system based on PET/CT image fusion

Feichtinger

Pau

Zemann

et al. 2010

Journal of Cranio-Maxillofacial Surgery

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Section: Discussionmentioning

confidence: 99%

Intraoperative control of resection margins in advanced head and neck cancer using a 3D-navigation system based on PET/CT image fusion

Feichtinger

Pau

Zemann

et al. 2010

Journal of Cranio-Maxillofacial Surgery

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“…The use of PET/CT scan to determine bony margins intraoperatively by surgical navigation has many advantages over histologic evaluation, including instant results. Feichtinger et al were the pioneers of image‐guided maxillofacial surgery 13. They also used PET/CT imaging intraoperatively in 3D surgical navigation for tumor ablation in advanced HNSCC with limited series.…”

Section: Discussionmentioning

confidence: 99%

A pilot study of segmental mandibulectomy with surgical navigation using fluorine‐18 fluorodeoxyglucose positron‐emission tomography/computed tomography

et al. 2012

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“…The advantages over standard CT or MRI alone are obvious: the surgeon is simultaneously equipped with a map of anatomical as well as functional (metabolic) details. The fused images offer improved detection of malignant lesions, especially for small lesions 5…”

Section: Discussionmentioning

confidence: 99%

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Itoh

Makiyama

Okanoue

2005

Cancer

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Objective Periventricular leukomalacia is the predominant type of brain injury in preterm infants underlying the development of cerebral palsy. Periventricular leukomalacia has its peak incidence at 23 to 32 weeks postconceptional age characterized by extensive oligodendrocyte migration and maturation. Oxygen toxicity has been identified as a possible contributing factor to the pathogenesis of cerebral palsy in survivors of preterm birth. 17β‐estradiol (E2) is important for the development and function of the central nervous system. Furthermore, neuroprotective properties have been attributed to estrogens. We examined the effect of E2 on hyperoxia‐induced cell death in the developing white matter in the rat brain. Methods Six‐day‐old (P6) rat pups, the immature oligodendroglial cell line (OLN‐93), and primary oligodendrocyte cultures were subjected to 80% O2 in the presence or absence of E2 (600μg/kg intraperitoneally in vivo, 10−6–10−10M in vitro). Cell counts and lactate dehydrogenase assay were used to assess cell survival. Immunoblot analysis was used for detection of estrogen receptor expression and investigation of apoptotic signaling pathways. White matter injury was assessed by myelin basic protein immunocytochemistry at P11. Results E2 produced significant dose‐dependent protection against oxygen‐induced apoptotic cell death in primary oligodendrocytes. Treatment with E2 prevented hyperoxia‐induced proapoptotic Fas‐upregulation and caspase‐3 activation. Finally, E2 antagonized hyperoxia‐induced inactivation of extracellular signal‐regulated kinase 1 and 2 and Akt, key kinases of the mitogen‐activated protein kinase and phosphatidylinositol 3‐kinase cell survival promoting pathways, respectively. Loss of myelin basic protein labeling was seen in P11 pups after oxygen exposure, and E2 attenuated this injury. Interpretation These results suggest a possible role for estrogens in the prevention of neonatal oxygen‐induced white matter injury. Ann Neurol 2007

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Case Report: Fusion of positron emission tomography (PET) and computed tomography (CT) images for image-guided endoscopic navigation in maxillofacial surgery: Clinical application of a new technique

Cited by 11 publications

References 32 publications

Intraoperative control of resection margins in advanced head and neck cancer using a 3D-navigation system based on PET/CT image fusion

Intraoperative control of resection margins in advanced head and neck cancer using a 3D-navigation system based on PET/CT image fusion

A pilot study of segmental mandibulectomy with surgical navigation using fluorine‐18 fluorodeoxyglucose positron‐emission tomography/computed tomography

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