Case report: intermittent fasting and probiotic yogurt consumption are associated with reduction of serum alpha-N-acetylgalactosaminidase and increased urinary excretion of lipophilic toxicants

Blythe, Jerry; Pacini, Stefania

doi:10.1101/177774

Cited by 3 publications

(1 citation statement)

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“…There is no doubt that our lifestyle leads to information that shapes the microbial information and viceversa. Such a reciprocal exchange of information was well described by Blythe and Pacini in a very recent report [11]. In this study, the Authors "describe the changes associated with three months of intermittent fasting and probiotic yogurt consumption in a 72-year-old marathon runner with chronic lymphocytic leukemia for a number of years".…”

Section: The Ship Of Theseusmentioning

confidence: 58%

The Human Microbiota and the Immune System; Reflections on Immortality

Ruggiero¹

2017

Madridge J Immunol

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In this Editorial I discuss implications arising from the novel interpretation of the human microbiota as integral part of the immune system with the ability to learn, memorize and have consciousness. The ship of Theseus as example of continuity as it relates to immortality is discussed. Finally, analogies between the human microbiota and the rhizome as proposed by Deleuze and Guattari are explored.

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Section: The Ship Of Theseusmentioning

confidence: 58%

The Human Microbiota and the Immune System; Reflections on Immortality

Ruggiero¹

2017

Madridge J Immunol

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The effects of time‐restricted eating alone or in combination with probiotic supplementation in comparison with a calorie‐restricted diet on endocrine and metabolic profiles in women with polycystic ovary syndrome: A randomized clinical trial

Talebi,

Shab‐Bidar,

Moini

et al. 2024

Diabetes Obesity Metabolism

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AimTo assess the impact of intermittent fasting, with or without probiotic supplementation, versus a calorie‐restricted diet on anthropometric measures, metabolic status and gonadal variables in women with polycystic ovary syndrome (PCOS).MethodsThis is a randomized, placebo‐controlled, parallel‐arm clinical trial. The effects of the 14:10 early time‐restricted eating (eTRE) strategy alone or combined with probiotics, on obese women with PCOS, were investigated. Participants were divided into three groups: eTRE plus probiotics (n = 30), eTRE plus placebo (n = 30) and a control group following a standard three‐meal‐per‐day diet with daily calorie restriction (DCR) (n = 30). Over 8 weeks, various anthropometric, metabolic, menstrual and gonadal variables were assessed.ResultsA total of 90 individuals were included in the study, with a mean body weight of 81.4 kg, and a mean age of 30 years. Mean (standard deviation) weight loss was not different between the groups at week 8 (TRE + probiotic: −2.2 [1.6] kg vs. TRE + placebo: −2.9 [2.7] kg vs. DCR: −2.5 [1.7] kg). Results revealed that, while all three regimes led to reductions in body weight, body mass index, vascular risk indicators, hirsutism and acne scores, there were no statistically significant differences between the eTRE groups and the control group in terms of weight loss, or improvements in metabolic, menstrual and gonadal variables (P > .05). Additionally, combining probiotics with eTRE did not benefit hormonal and cardiometabolic factors (P > .05).ConclusionsThe eTRE alone or eTRE plus probiotics did not result in significantly greater weight loss or improvements in metabolic, menstrual and gonadal variables compared with the standard three‐meal DCR diet.

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From neurology to oncology: what have in common autism and cancer? the role of oncogenes, immune system and microbiota

Ruggiero¹,

Pacini²

2018

JNSK

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Autism and cancer are the products of complex interactions between genetic and environmental factors, for the most part yet unclarified in autism, better characterized in cancer. Even though autism and cancer may appear as two separate conditions with nothing in common, they share a conspicuous number of similarities at the level of pathogenesis that may be useful for translating preventive and therapeutic approaches from one disease to the other. Oncogene-associated signaling appears to play an adaptive or compensatory role in autism in contrast with cancer where it is one of the culprits for initiation of the disease. Immunological deficiencies and chronic inflammation are present in both diseases, and approaches aimed at balancing the immune system and reducing inflammation are useful in prevention and treatment of both. Alterations of the microbiota have a causative role in autism whereas in cancer it is yet to be determined whether they are causes or effects of the disease.

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Case report: intermittent fasting and probiotic yogurt consumption are associated with reduction of serum alpha-N-acetylgalactosaminidase and increased urinary excretion of lipophilic toxicants

Cited by 3 publications

References 25 publications

The Human Microbiota and the Immune System; Reflections on Immortality

The Human Microbiota and the Immune System; Reflections on Immortality

The effects of time‐restricted eating alone or in combination with probiotic supplementation in comparison with a calorie‐restricted diet on endocrine and metabolic profiles in women with polycystic ovary syndrome: A randomized clinical trial

From neurology to oncology: what have in common autism and cancer? the role of oncogenes, immune system and microbiota

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