Case report: Life‐threatening bronchospasm after intramuscular carboprost for postpartum haemorrhage

Harber, CR; Levy, DM; Chidambaram, Swathikan; Macpherson, MB

doi:10.1111/j.1471-0528.2006.01227.x

Cited by 27 publications

(13 citation statements)

References 7 publications

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“…Caution must be exercised in the presence of maternal hypertension, asthma, cardiac disease, impaired pulmonary, renal or hepatic function. Severe bronchospasm may occur even in those without asthma (Harber et al 2007). …”

Section: Prostaglandinsmentioning

confidence: 98%

Operative interventions in the management of major postpartum haemorrhage

Keriakos

Chaudhuri

2011

Journal of Obstetrics and Gynaecology

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In many recent studies in the developed world, the incidence of postpartum haemorrhage (PPH) has been rising, though the mortality has come down, suggesting improvement in the management of this condition. Since the publication of the RCOG guidelines in 2009 for management of PPH and the Sheffi eld guidelines for the use of Rusch balloon along with the initial small case series (Keriakos and Mukhopadhyay 2006), many units have introduced the guidelines into clinical practice. This has led to the reduction of surgical intervention in our unit. Major PPH accounted for 1.6% of the total deliveries in our hospital. Surgical interventions accounted for 7.8% of these cases and only 0.1% of the total deliveries. Risk factors for PPH were identifi ed in 83%. In this paper, we reviewed the management of all patients who had major PPH and failed medical management over a period of about 4 years. All surgical interventions including Rusch balloon, B-Lynch suture, radiological interventions and hysterectomy were described. An update to Rusch balloon guidelines and Sheffi eld guidelines for management of major PPH are appended.

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Section: Prostaglandinsmentioning

confidence: 98%

Operative interventions in the management of major postpartum haemorrhage

Keriakos

Chaudhuri

2011

Journal of Obstetrics and Gynaecology

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“…It should be used with caution in asthma, hypertension, hypotension, anaemia, jaundice, diabetes, epilepsy and uterine scars, and is contraindicated in cardiac, renal, pulmonary or hepatic disease. Common side-effects include bronchospasm (Harber et al 2007;Cooley et al 1991). Less frequent side-effects include pulmonary oedema, among others.…”

Section: Discussionmentioning

confidence: 98%

A case of pulmonary oedema secondary to carboprost

Barney¹,

Haughney²,

Bilolikar³

2012

Journal of Obstetrics and Gynaecology

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“…Hemabate (250 mg intramuscularly or intramyometrially) is a potent smooth muscle constrictor and contracts the uterus well. It can, however, cause significant bronchospasm, which may be life threatening as reported by Harber et al [18]. The use of misoprostol (PGE 2 ) appears to be increasing and has recently been the subject of many reviews.…”

Section: Pharmacologicalmentioning

confidence: 93%