Case Report. Multiple etiology post‐surgery endophthalmitis

Vescia, N; Cavarischia, R.; Valente, Anne Marie; Fabiani, Massimo; Melchionda, C; Mastroeni, I

doi:10.1046/j.0933-7407.2001.00690.x

Cited by 5 publications

(5 citation statements)

References 8 publications

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“…A review of the medical literature revealed 19 cases of ophthalmic infections involving C glabrata or T glabrata (Delany CM, et al IOVS 2003; 44:ARVO E-Abstract 1396). [1][2][3][4][5][6][15][16][17][18][19] A disproportionately large number of these cases (9) were endophthalmitis that occurred following PKP (Table 1). [1][2][3][4][5][6][7][8][9] After the first case of post-keratoplasty C glabrata endophthalmitis was reported in 1978, only 2 were reported until 1998.…”

Section: Discussionmentioning

confidence: 99%

“…[5][6][7] Besides the cases of post-keratoplasty endophthalmitis, C glabrata has been reported in a relatively few isolated cases of keratitis, post-cataract endophthalmitis, and endogenous chorioretinitis (Delany CM, et al IOVS 2003; 44:ARVO E-Abstract 1396). [15][16][17][18][19][20][21] It is not clear why C glabrata is most commonly associated with PKP, but several factors are likely to be important. Fungal infections, on the rise as a whole, are associated with the use of immunosuppression and broad-spectrum antibiotic agents, both of which are used therapeutically in corneal transplant patients.…”

Section: Discussionmentioning

confidence: 99%

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Candida glabrata endophthalmitis following penetrating keratoplasty

Caldwell

Perfect

Carlson

et al. 2009

Journal of Cataract and Refractive Surgery

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We report a case of Candida glabrata endophthalmitis following penetrating keratoplasty in a 57-year-old man. The infection was thought to be treated successfully with intravitreal amphotericin B but flared 7 months later following cataract extraction and eventually required explantation of the intraocular lens and therapeutic keratoplasty. The literature regarding this rare infection is reviewed. Candida glabrata, an uncommon ocular pathogen, is being reported with increasing frequency and with a notable predilection for post-keratoplasty eyes. In the 10 reported cases, there is 100% concordance between host and donor tissue cultures. In half the cases, there was a latent period of several months. These infections can be difficult to treat because C glabrata is often resistant to the antifungal agents commonly used to treat Candida albicans.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Candida glabrata endophthalmitis following penetrating keratoplasty

Caldwell

Perfect

Carlson

et al. 2009

Journal of Cataract and Refractive Surgery

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“…The initial symptoms of Acremonium endophthalmitis are similar to those of most delayed-onset endophthalmitis, including mild pain, redness, floaters and slightly decreased visual acuity [ 7 - 10 ]. The interval between surgery and endophthalmitis onset ranges from two to six weeks [ 12 ].…”

Section: Discussionmentioning

confidence: 99%

Post-operative endophthalmitis caused by Acremonium falciforme with orbital and extra-orbital involvement following combined cataract and glaucoma surgery: a case report

et al. 2014

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IntroductionIn this report, we describe an unusual case of post-operative Acremonium falciforme endophthalmitis with orbital and extra-orbital involvement following combined cataract and glaucoma surgery.Case presentationA 68-year-old Caucasian man with glaucoma presented with endophthalmitis characterized by pain, redness and impaired vision in the left eye fifteen days after combined cataract and filtering surgery. He subsequently underwent a pars plana vitrectomy, with vitreous sampling, silicone oil placement and intra-vitreal injection of antibiotics, but only after a second vitrectomy we identified Acremonium falciforme as the causative agent for the endophthalmitis. An antifungal systemic and topical therapy was started, but meanwhile the infection extended to orbital and peri-orbital tissues. Following these procedures, even if the eye went slowly in phthisis, we were able to limit the further extension and circumscribe the orbital and extra-orbital involvement.ConclusionTo our knowledge, this report is the first describe Acremonium falciforme endophthalmitis with orbital and extra-orbital involvement, following anterior segment combined surgery. Ophthalmologists and physicians should be aware of the extension risk of a fungal panophthalmitis, but also to potentially serious side effects related to systemic therapy.

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“…The initial presenting symptoms of Acremonium endophthalmitis are similar to those of most delayed-onset fungal endophthalmitis, including mild pain, redness, floaters and slightly decreased visual acuity [2-5,7]. The time interval between cataract operation and endophthalmitis ranges from 12 days to six weeks, but is usually one month [2-5,7].…”

Section: Discussionmentioning

confidence: 99%

“…The time interval between cataract operation and endophthalmitis ranges from 12 days to six weeks, but is usually one month [2-5,7]. Interestingly, Acremonium infection may mimic Propionibacterium infection in that both organisms yield similar plaque-like materials in and around the anterior chamber [2-4].…”

Section: Discussionmentioning

confidence: 99%

Case Report of Acremonium Intraocular Infection after Cataract Extraction

Joe

Lim

Lee

et al. 2010

Korean J Ophthalmol

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A 64-year-old woman was referred to our clinic for the treatment of chronic uveitis in her left eye, which had started two weeks after an uncomplicated cataract extraction. She was treated with topical steroids with an initially good response, yet she subsequently developed severe inflammation and plaque-like material around the intraocular lens, despite continuous steroid therapy. She underwent pars plana vitrectomy, smear and culture of the aqueous and vitreous fluids, and intravitreal antibiotic injection under the impression of Propionibacterium acne (P. acne) endophthalmitis. As a result of the smear and culture of the vitreous fluid identified as an Acremonium species, she was treated with intravenous amphotericin B injections for five days, followed by oral voriconazole administration. During the post-operative 18-month follow-up, she was stable without significant relapse of uveitis. In this case, the best correction of visual acuity was an improvement from 20/40 to 20/20.

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Case Report. Multiple etiology post‐surgery endophthalmitis

Cited by 5 publications

References 8 publications

Candida glabrata endophthalmitis following penetrating keratoplasty

Candida glabrata endophthalmitis following penetrating keratoplasty

Post-operative endophthalmitis caused by Acremonium falciforme with orbital and extra-orbital involvement following combined cataract and glaucoma surgery: a case report

Case Report of Acremonium Intraocular Infection after Cataract Extraction

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