Case report Multiple schwannomas of the digital nerves and superficial radial nerve: two unusual cases of segmental schwannomatosis

Gosk, Jerzy; Gutkowska, Olga; Kuliński, Sebastian; Urban, Maciej; Hałoń, Agnieszka

doi:10.5114/fn.2015.52413

Cited by 14 publications

(12 citation statements)

References 36 publications

(59 reference statements)

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“…Most often these tumors are solitary but can occur in multiple areas also. Multiple occurrences are usually associated not only with neurofibromatosis II but also schwannomatosis [ 4 , 5 ]. Head and neck are the most commonly affected regions (25–45%) with the lateral neck being the frequently involved site [ 6 , 7 ].…”

Section: Discussionmentioning

confidence: 99%

Head and Neck Schwannomas: A Surgical Challenge—A Series of 5 Cases

Ansari

Graison

et al. 2018

Case Reports in Otolaryngology

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Background Schwannomas, also known as neurilemmomas, are benign peripheral nerve sheath tumors. They originate from any nerve covered with schwann cell sheath. Schwannomas constitute 25–45% of tumors of the head and neck. About 4% of head and neck schwannomas present as a sinonasal schwannoma. Brachial plexus schwannoma constitute only about 5% of schwannomas. Cervical vagal schwannomas constitute about 2–5% of neurogenic tumors. Methods We present a case series of 5 patients of schwannomas, one arising from the maxillary branch of trigeminal nerve in the maxillary sinus, second arising from the brachial plexus, third arising from the cervical vagus, and two arising from cervical spinal nerves. Result Complete extracapsular excision of the tumors was achieved by microneurosurgical technique with preservation of nerve of origin in all except one. Conclusion Head and neck schwannoma though rare should be considered as a differential diagnosis of a unilateral slow growing mass in the head and neck region, particularly in an adult. Schwannomas are always a diagnostic dilemma as they are asymptomatic for long time, and histopathology is the gold standard for diagnosis. As a rule, treatment is surgical and dictated by the location of the tumor and nerve of origin. Due to its rarity, complex anatomical location and morbidity risk postexcision, they can pose a formidable challenge to surgeons. This study aims to describe the presentation, workup, surgical technique, and outcome.

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Section: Discussionmentioning

confidence: 99%

Head and Neck Schwannomas: A Surgical Challenge—A Series of 5 Cases

Ansari

Graison

et al. 2018

Case Reports in Otolaryngology

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“…• Confusion with NF2, presumptive schwannomatosis, 4 and familial schwannomatosis [23][24][25] • Two studies 2,26 were performed before the release of the 2005 consensus statement, 1 and other studies did not ensure the patients met the criteria for definite schwannomatosis, particularly regarding the lack of systematic brain MRI to formally eliminate NF2, [26][27][28] being < 18 years of age at diagnosis, 25,[29][30][31][32][33] and the presence of intracranial lesions 34,35 • Two studies were original articles with no individual descriptive cases 1,36 Approximately 10 to 15% of patients with schwannomatosis have a family history. 17,37 The remaining 85 to 90% have sporadic disease.…”

Section: Discussionmentioning

confidence: 99%

Sporadic Schwannomatosis: A Systematic Review Following the 2005 Consensus Statement

Chick

Victor

Poujade

et al. 2018

J Neurol Surg A Cent Eur Neurosurg

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This systematic review quantified the number of individuals who meet the criteria for sporadic schwannomatosis and better described this population to facilitate the classification of neurofibromatosis in regard to the 2005 consensus statement. Unilateral or segmental distribution of nerve tumors are key aspects when dealing with multiple noncutaneous schwannomas without involvement of the vestibular nerve.

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“…5 % der Fälle kann die Tumormasse als sogenanntes plexiformes Schwannom eine unregelmäßige, multinoduläre Form aufweisen [9]. Selten, aber bereits mehrfach beschrieben, ist das Auftreten multipler Schwannome im Verlauf eines Nervs und seiner Äste oder auch an verschiedenen Nerven derselben Extremität (Schwannomatose) [3,[10][11][12][13][14][15]. Im Allgemeinen ist nur eine Körperhälfte betroffen.…”

Section: Introductionunclassified