Case report of a Saccharomyces cerevisiae lung parenchyma infection in an immunocompetent 64-year-old male with a Zenker diverticulum

Abstract

Saccharomyces cerevisiae is a yeast microorganism known to inhabit the gut micro-biome. It is commonly used in the fermentation process of beer, wine, bread making, and is naturally found in soil, plants, and fruit. Saccharomyces boulardii (subtype of Saccharomyces) and cerevisiae are closely related and are commonly used as a probiotic and in treatment for diarrhea. In rare circumstances, Saccharomyces has been shown to cause infection in the immunocompromised and intensive care unit (ICU) patients, with antibiotic use, and central venous catheter use. This prompts us to present one of the only documented case reports of a lung parenchyma infection with Saccharomyces cerevisiae in a 64-year-old immunocompetent male with a past medical history of chronic obstructive pulmonary disorder (COPD), atrial fibrillation, atrioventricular (AV) nodal ablation, heart failure with preserved ejection fraction (HFrEF (post-status automated implantable cardioverter-defibrillator)), coronary artery bypass graft (CABG), gastric esophageal reflux disease (GERD), and a Zenker diverticulum.

Antifungal Activity of Medicinal Herbs Aqueous Extracts: Common Wormwood (Artemisia Absinthium L.), Greater Burdock (Arctium Lappa L.), Common Thyme (Thymus Vulgaris L.) and Pot Marigold (Calendula Officinalis L.) on Yeast Saccharomyces Cerevisiae

“…There are known cases where the fungus Saccharomyces cerevisiae was discovered in people whose professional activities were associated with regular stays in various bakeries and caused lung disease. It is believed that the source of infection in this case was inhalation of dry yeast powder [9]. In rare cases, Saccharomyces cerevisiae causes invasive infections infecting the main bloodstream or other body fluids that should normally be sterile, or internal organs, such as the lungs, liver, and spleen.…”