Case report: Orbital epithelioid haemangioendothelioma

Zaragoza-Herrera, A.; Morales-Baños, D.R.; Velasco-Ramos, P.; Garrido-Sánchez, Gildardo Agustín; López-Hernández, C.M.; Borbolla-Pertierra, A.M.

doi:10.1016/j.oftale.2016.07.005

Cited by 1 publication

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“…Since 2002, the WHO has classified EH as a malignancy (2,3). EH occurs in superficial or deep soft tissues such as those of the extremities, liver, lungs and bone, and rarely in the orbit and/or eyelids (4,5). Since Tsuji et al (6) first reported EHE in 2010, to the best of our knowledge, only 4 cases have been reported worldwide (6)(7)(8)(9).…”

Section: Discussionmentioning

confidence: 99%

“…Since 2002, the World Health Organization (WHO) has classified EH as a malignant tumor (2,3). EH occurs in the superficial or deep soft tissues of the limbs, liver, lungs and bones, among others, and rarely occurs in the orbit and/or eyelid (4,5). EH can occur at any age, with cases occurring in patients between 13 and 86 years old, with a median age of ~50 years.…”

Section: Introductionmentioning

confidence: 99%

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Primary epithelioid hemangioendothelioma of the eyelid: A case report

et al. 2022

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Eyelid epithelioid hemangioendothelioma (EHE) is uncommon. The present study reports the clinical, histopathological and immunohistochemical characteristics of a 10-year-old girl with EHE and reviews the related literature. The patient was admitted with a painless red mass on the left eyelid, which had been present for 6 months. Under the microscope, tumor cells from the surgical specimen were composed of epithelioid cells (70%) and spindle cells (30%). The cytoplasm was eosinophilic, and some areas of the cytoplasm showed signet ring-like or vacuolization changes. The presence of red blood cells could be seen in the luminal part of the primary blood vessel. Immunohistochemical results showed that the tumor cells were positive for CD34 and CD31, and the Ki-67 proliferation index was 3%. As the first resection margin was positive, recurrence occurred 3 months after surgery, Therefore, patients with such tumors should undergo full resections to ensure a negative margin to prevent recurrence.

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