2021
DOI: 10.3389/fpsyt.2020.529672
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Case Report: Paliperidone Palmitate in the Management of Bipolar I Disorder With Non-compliance

Abstract: Background: Medication non-adherence is prevalent in patients with bipolar disorder (BD). Long-acting injectable antipsychotics (LAIAs) are widely used to improve compliance with treatment. This study aimed to illustrate the effectiveness, compliance, and safety profile of once-monthly paliperidone palmitate (PP1M), a novel therapeutic LAIA, in the management of bipolar I disorder (BDI).Method: A prospective follow-up was arranged to 11 BDI patients who were prescribed PP1M as monotherapy or adjunctive treatme… Show more

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“…Paliperidone long-acting injections (PPLAIs) are effective in maintenance treatment of adults with schizophrenia and licensed for this use in most of the world. There are relatively limited reports of one monthly paliperidone (PP1M) use in schizoaffective disorder [1][2][3] or bipolar disorder [3][4][5]. These studies do however support their value in reducing hospital admissions and the number of manic or mixed episodes, and the risk of relapse and hospitalization.…”
Section: Introductionmentioning
confidence: 99%
“…Paliperidone long-acting injections (PPLAIs) are effective in maintenance treatment of adults with schizophrenia and licensed for this use in most of the world. There are relatively limited reports of one monthly paliperidone (PP1M) use in schizoaffective disorder [1][2][3] or bipolar disorder [3][4][5]. These studies do however support their value in reducing hospital admissions and the number of manic or mixed episodes, and the risk of relapse and hospitalization.…”
Section: Introductionmentioning
confidence: 99%